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定制 Bowman 基质嵌片:改变圆锥角膜地形的尝试。

Customized Bowman-Stromal Inlay: An Attempt to Change the Topography of the Keratoconus Cornea.

机构信息

Cornea and Anterior Segment Services, L J Eye Institute, 251, Model Town, Ambala, Haryana 134002, India.

出版信息

Cornea. 2023 Jun 1;42(6):739-743. doi: 10.1097/ICO.0000000000003257. Epub 2023 Mar 28.

Abstract

PURPOSE

The objective of this report is to describe a modification of a previously reported technique with an aim of improving the corneal topography and visual outcomes in progressive keratoconus along with stabilization of ectasia.

METHOD

In a 26-year-old man with progressive keratoconus, corneal collagen cross-linking was performed in one eye. The other eye had a keratometry of 69.6 D and thinnest pachymetry of 397 µm for which a customized Bowman-stromal inlay surgery was performed. The technique involved the harvesting of Bowman-stromal inlay (anterior 180-μm human donor cornea having the Bowman's layer and anterior stroma) using the femtosecond laser and central ablation of this inlay was done on the stromal side using an excimer laser. This customized inlay was placed in the anterior stromal pocket of the patient's cornea using a regular intraocular lens injector.

RESULTS

Stabilization of keratoconus could be achieved in the present case along with improvement in the corrected distance visual acuity and pachymetry. Maximum keratometry decreased from 69.6 D to 57.3 D.

CONCLUSIONS

Customized Bowman-stromal inlay technique appears to be a step towards creating an ideal inlay for the keratoconus cornea.

摘要

目的

本报告旨在描述一种先前报道技术的改良方法,旨在改善进行性圆锥角膜的角膜地形和视觉结果,并稳定角膜扩张。

方法

在一名 26 岁的进行性圆锥角膜患者中,一只眼进行了角膜胶原交联。另一只眼的角膜曲率计读数为 69.6 D,最薄的角膜厚度为 397 µm,因此对其进行了定制的 Bowman 基质镶嵌术。该技术涉及使用飞秒激光采集 Bowman 基质镶嵌(具有 Bowman 层和前基质的 180 µm 人供体角膜),并使用准分子激光在前基质侧对该镶嵌进行中央消融。将这个定制的镶嵌物使用常规的眼内透镜注射器放置在患者角膜的前基质口袋中。

结果

本病例中成功稳定了圆锥角膜,同时改善了矫正视力和角膜厚度。最大角膜曲率计读数从 69.6 D 降低至 57.3 D。

结论

定制的 Bowman 基质镶嵌术似乎是为圆锥角膜角膜创建理想镶嵌物的一个步骤。

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