Manjaly Priya, Xia Eric, Allan Alexandra, Vinjamuri Shreya, Garza Henriette De La, Manjaly Cyriac, Szeto Mindy D, Eichstadt Shaundra, Maymone Mayra, Vashi Neelam
Department of Dermatology, Boston University School of Medicine, Boston, Massachusetts, USA.
Department of Internal Medicine, MetroWest Medical Center, Framingham, Massachusetts, USA.
J Cosmet Dermatol. 2023 Sep;22(9):2434-2439. doi: 10.1111/jocd.15739. Epub 2023 Mar 28.
In cosmetic dermatology, lasers and lights treat a variety of hair and skin conditions, including some that disproportionately affect people of color.
Our systematic review aims to understand the representation of participants with skin phototypes 4-6 in cosmetic dermatologic trials studying laser and light devices.
A systematic literature search was conducted using search terms "laser," "light," and multiple laser and light subtypes in the PubMed and Web of Science databases. All randomized controlled trials (RCTs) published between January 1, 2010 and October 14, 2021 that studied laser or light devices for cosmetic dermatologic conditions were eligible for inclusion.
Our systematic review included 461 RCTs representing 14 763 participants. Of 345 studies that reported skin phototype, 81.7% (n = 282) included participants of skin phototypes 4-6, but only 27.5% (n = 95) included participants of skin phototypes 5 or 6. This trend of excluding darker skin phototypes persisted when results were stratified by condition, laser of study, study location, journal type, and funding source.
Trials studying lasers and lights for the treatment of cosmetic dermatologic conditions need better representation of skin phototypes 5 and 6.
在美容皮肤科中，激光和光可治疗多种毛发和皮肤疾病，包括一些对有色人种影响尤为严重的疾病。
我们的系统评价旨在了解在研究激光和光设备的美容皮肤科试验中，皮肤光型为4 - 6型的参与者的代表性情况。
在PubMed和Web of Science数据库中使用搜索词“激光”“光”以及多种激光和光的亚型进行系统文献检索。所有在2010年1月1日至2021年10月14日期间发表的、研究用于美容皮肤科疾病的激光或光设备的随机对照试验（RCT）均符合纳入标准。
我们的系统评价纳入了461项RCT，涉及14763名参与者。在345项报告了皮肤光型的研究中，81.7%（n = 282）纳入了皮肤光型为4 - 6型的参与者，但只有27.5%（n = 95）纳入了皮肤光型为5或6型的参与者。当按疾病、研究的激光类型、研究地点、期刊类型和资金来源对结果进行分层时，排除深色皮肤光型的这一趋势依然存在。
研究用于治疗美容皮肤科疾病的激光和光的试验需要更好地纳入皮肤光型为5和6型的参与者。
