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原发性甲状旁腺功能亢进症伴严重视力丧失患者的脉络膜巩膜钙化伴视神经钙化。

SCLEROCHOROIDAL CALCIFICATION WITH OPTIC NERVE CALCIFICATION IN A PATIENT WITH PRIMARY HYPERPARATHYROIDISM AND SEVERE VISION LOSS.

机构信息

Department of Ophthalmology, Georgetown University School of Medicine, Washington, D.C.; and.

Florida Retina Consultants, Lakeland, Florida.

出版信息

Retin Cases Brief Rep. 2024 Jul 1;18(4):499-502. doi: 10.1097/ICB.0000000000001418.

DOI:10.1097/ICB.0000000000001418
PMID:36977331
Abstract

BACKGROUND/PURPOSE: To present a case of sclerochoroidal calcification (SCC) associated with dural calcification along the optic nerves and severe visual loss.

METHODS

Case report.

RESULTS

A 74-year-old white female patient with a 25-year history of primary hyperparathyroidism and surgical removal of a single parathyroid gland presented with blurred vision. On presentation, she had a calcium level of 12.6 mg/dL (reference range: 8.7-10.3 mg/dL). Her best-corrected visual acuity (BCVA) was 20/40 in both eyes, and she was diagnosed with bilateral SCC. After 2 years, the patient returned with a complaint of progressive vision loss, and the BCVA was 20/150 in the right eye and hand motion in the left eye. She had stable focal SCC on fundus examination with no significant changes from the previous examination. The fluorescein angiogram was unremarkable with no leakage. Optical coherence tomography (OCT) of the macula showed no edema or subretinal fluid and was not significantly changed from the first OCT. B-scan showed areas of calcification in the sclera consistent with the SCC. Computerized tomography (CT) scans showed dural calcifications along both optic nerves. She had no enlargement of SCC lesions and no other ocular or neurologic pathology associated with her vision loss.

CONCLUSION

We present a patient with bilateral SCC and associated calcification in both globes. Unlike previous reports of SCC, our case demonstrated progressive severe vision loss because of dural calcification along the optic nerves. Patients with SCC and decreased vision should receive a CT scan to look for this rare associated finding.

摘要

背景/目的:介绍一例与视神经硬脑膜钙化相关的硬化性脉络膜骨化(SCC)病例,伴有严重视力丧失。

方法

病例报告。

结果

一名 74 岁白人女性,原发性甲状旁腺功能亢进病史 25 年,曾行单侧甲状旁腺切除术,因视力模糊就诊。就诊时,血钙水平为 12.6mg/dL(参考范围:8.7-10.3mg/dL)。最佳矫正视力(BCVA)为双眼 20/40,诊断为双侧 SCC。2 年后,患者因视力进行性下降而返回,右眼 BCVA 为 20/150,左眼手动视力。眼底检查发现稳定的局灶性 SCC,与前一次检查相比无明显变化。荧光素血管造影无渗漏,无明显异常。黄斑 OCT 显示无水肿或视网膜下液,与第一次 OCT 相比无明显变化。B 型扫描显示巩膜有钙化区,符合 SCC。计算机断层扫描(CT)显示双侧视神经硬脑膜钙化。SCC 病变无增大,也无其他与视力丧失相关的眼部或神经病理学改变。

结论

我们报告了一例双侧 SCC 伴双侧眼球钙化的病例。与以往 SCC 报告不同,我们的病例因视神经硬脑膜钙化而表现出进行性严重视力丧失。SCC 伴视力下降的患者应行 CT 扫描以寻找这种罕见的相关发现。

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