Fuller H D
Can Anaesth Soc J. 1986 Mar;33(2):213-5. doi: 10.1007/BF03010833.
A case is presented of asymptomatic cyanosis of the hands, seen four hours after dental surgery under intravenous, local and inhalational anaesthesia. Alphaprodine hydrochloride, a synthetic opiate and one of the agents used, may produce dilatation of the venous bed with passive venous pooling. Such a mechanism is thought to have occurred in this case, manifesting as cyanosis. A weakly positive intradermal skin test to alphaprodine suggests immediate type hypersensitivity as a possible underlying cause.
本文报告了一例在静脉、局部和吸入麻醉下进行牙科手术后4小时出现的手部无症状性发绀病例。盐酸阿法罗定是一种合成阿片类药物，也是所使用的药物之一，它可能导致静脉床扩张并伴有被动性静脉淤血。据认为，该病例就出现了这样的机制，表现为发绀。对阿法罗定的皮内皮肤试验呈弱阳性，提示速发型超敏反应可能是潜在病因。
