Wanjala George, Astuti Putri Kusuma, Bagi Zoltán, Kichamu Nelly, Strausz Péter, Kusza Szilvia
Centre for Agricultural Genomics and Biotechnology, Faculty of Agricultural and Food Sciences and Environmental Management, University of Debrecen, 4032 Debrecen, Hungary.
Doctoral School of Animal Science, University of Debrecen, 4032 Debrecen, Hungary.
Biology (Basel). 2023 Feb 28;12(3):386. doi: 10.3390/biology12030386.
Dorper sheep was developed for meat production in arid and semi-arid regions under extensive production systems in South Africa. Two variants with distinct head and neck colors were bred during their development process. White Dorper have a white coat while Dorper have a black head and neck. Both variants have grown in popularity around the world. Therefore, understanding the genomic architecture between South African Dorpers and Dorper populations adapted to other climatic regions, as well as genomic differences between Dorper and White Dorper variants is vital for their molecular management. Using the ovine 50K SNP chip, this study compared the genetic architecture of Dorper variants between populations from South Africa and Hungary. The Dorper populations in both countries had high genetic diversity levels, although Dorper in Hungary showed high levels of inbreeding. White Dorpers from both countries were genetically closely related, while Dorpers were distantly related according to principal component analysis and neighbor-joining tree. Additionally, whereas all groups displayed unique selection signatures for local adaptation, Dorpers from Hungary had a similar linkage disequilibrium decay. Environmental differences and color may have influenced the genetic differentiation between the Dorpers. For their molecular management and prospective genomic selection, it is crucial to understand the Dorper sheep's genomic architecture, and the results of this study can be interpreted as a step in this direction.
杜泊羊是在南非粗放型生产系统下，为干旱和半干旱地区的肉类生产而培育的。在其培育过程中，繁育出了两种头部和颈部颜色不同的变种。白杜泊羊全身被毛为白色，而杜泊羊头部和颈部为黑色。这两个变种在世界各地都越来越受欢迎。因此，了解南非杜泊羊与适应其他气候区域的杜泊羊群体之间的基因组结构，以及杜泊羊变种和白杜泊羊变种之间的基因组差异，对它们的分子管理至关重要。本研究使用绵羊50K SNP芯片，比较了南非和匈牙利群体中杜泊羊变种的遗传结构。两国的杜泊羊群体都具有较高的遗传多样性水平，不过匈牙利的杜泊羊显示出较高的近亲繁殖水平。根据主成分分析和邻接树，来自两国的白杜泊羊在基因上密切相关，而杜泊羊则关系较远。此外，虽然所有群体都表现出适应本地环境的独特选择特征，但匈牙利的杜泊羊具有相似的连锁不平衡衰减。环境差异和毛色可能影响了杜泊羊之间的遗传分化。对于它们的分子管理和未来的基因组选择而言，了解杜泊羊的基因组结构至关重要，本研究结果可被视为朝着这个方向迈出的一步。
