一种评估被记录为“死于其他原因”的癌症患者潜在偏倚的方法。在眼内黑色素瘤病例中的应用。

A method for assessing potential bias among cancer patients recorded as "dead of other causes." Application to cases of intraocular melanoma.

作者信息

Gamel J, Seddon J, Polivogianis L, Albert D, Greenberg R

出版信息

Cancer. 1986 Jun 1;57(11):2246-9. doi: 10.1002/1097-0142(19860601)57:11<2246::aid-cncr2820571130>3.0.co;2-3.

DOI:10.1002/1097-0142(19860601)57:11<2246::aid-cncr2820571130>3.0.co;2-3

Abstract

By applying the Cox regression model to 226 cases of intraocular melanoma, the authors detected a statistical association between tumor-related measurements and 42 deaths that were recorded as due to causes other than melanoma within 10 years of follow-up. This association may reflect a number of events, including errors in assignment of cause of death and confounding from any one of several sources.

摘要

通过将Cox回归模型应用于226例眼内黑色素瘤患者，作者发现肿瘤相关测量指标与42例死亡之间存在统计学关联，这些死亡被记录为在随访的10年内因黑色素瘤以外的原因所致。这种关联可能反映了多种情况，包括死因分配错误以及来自多个来源中任何一个的混杂因素。