Tamai Koji, Terai Hidetomi, Nakamura Hiroaki, Yokogawa Noriaki, Sasagawa Takeshi, Nakashima Hiroaki, Segi Naoki, Ito Sadayuki, Funayama Toru, Eto Fumihiko, Yamaji Akihiro, Watanabe Kota, Yamane Junichi, Takeda Kazuki, Furuya Takeo, Yunde Atsushi, Nakajima Hideaki, Yamada Tomohiro, Hasegawa Tomohiko, Terashima Yoshinori, Hirota Ryosuke, Suzuki Hidenori, Imajo Yasuaki, Ikegami Shota, Uehara Masashi, Tonomura Hitoshi, Sakata Munehiro, Hashimoto Ko, Onoda Yoshito, Kawaguchi Kenichi, Haruta Yohei, Suzuki Nobuyuki, Kato Kenji, Uei Hiroshi, Sawada Hirokatsu, Nakanishi Kazuo, Misaki Kosuke, Kuroda Akiyoshi, Inoue Gen, Kakutani Kenichiro, Kakiuchi Yuji, Kiyasu Katsuhito, Tominaga Hiroyuki, Tokumoto Hiroto, Iizuka Yoichi, Takasawa Eiji, Akeda Koji, Takegami Norihiko, Funao Haruki, Oshima Yasushi, Kaito Takashi, Sakai Daisuke, Yoshii Toshitaka, Ohba Tetsuro, Otsuki Bungo, Seki Shoji, Miyazaki Masashi, Ishihara Masayuki, Okada Seiji, Imagama Shiro, Kato Satoshi
Department of Orthopaedic Surgery, Osaka Metropolitan University Graduate School of Medicine, 1-4-3 Asahimachi, Abeno-ku, Osaka-City, Osaka 545-8585, Japan.
Department of Orthopaedic Surgery, Graduate School of Medical Sciences, Kanazawa University, 13-1 Takara-machi, Kanazawa, Ishikawa 920-8641, Japan.
J Clin Med. 2023 Mar 20;12(6):2387. doi: 10.3390/jcm12062387.
The number of elderly patients with cervical trauma is increasing. Such patients are considered to be at high risk for delirium, which is an acute neuropsychological disorder that reduces the patient's capacity to interact with their environment due to impairments in cognition. This study aimed to establish a risk score that predicts delirium in elderly patients with cervical SCI and/or cervical fracture regardless of treatment type. This retrospective cohort study included 1512 patients aged ≥65 years with cervical SCI and/or cervical fracture. The risk factors for delirium according to treatment type (surgical or conservative) were calculated using multivariate logistic regression. A delirium risk score was established as the simple arithmetic sum of points assigned to variables that were significant in the multivariate analyses. Based on the statistical results, the delirium risk score was defined using six factors: old age (≥80 years), hypoalbuminemia, cervical fracture, major organ injury, dependence on pre-injury mobility, and comorbid diabetes. The score's area under the curve for the prediction of delirium was 0.66 ( < 0.001). Although the current scoring system must be validated with an independent dataset, the system remains beneficial because it can be used after screening examinations upon hospitalization and before deciding the treatment strategy.
老年颈椎创伤患者的数量正在增加。这类患者被认为发生谵妄的风险很高,谵妄是一种急性神经心理障碍,由于认知障碍会降低患者与周围环境互动的能力。本研究旨在建立一个风险评分系统,用于预测老年颈椎脊髓损伤(SCI)和/或颈椎骨折患者(无论治疗类型如何)发生谵妄的风险。这项回顾性队列研究纳入了1512例年龄≥65岁的颈椎SCI和/或颈椎骨折患者。采用多因素logistic回归分析计算不同治疗类型(手术或保守治疗)患者发生谵妄的危险因素。将多因素分析中有统计学意义的变量所对应的分值进行简单算术相加,从而建立谵妄风险评分。根据统计结果,谵妄风险评分由六个因素确定:高龄(≥80岁)、低白蛋白血症、颈椎骨折、主要器官损伤、伤前活动依赖以及合并糖尿病。该评分预测谵妄的曲线下面积为0.66(P<0.001)。尽管目前的评分系统必须通过独立数据集进行验证,但该系统仍然是有益的,因为它可以在患者住院筛查后、决定治疗策略前使用。