Fiedorek S C, Shulman R J, Klish W J
Clin Pediatr (Phila). 1986 May;25(5):243-6. doi: 10.1177/000992288602500501.
Abdominal pain is common among cystic fibrosis (CF) patients and may be caused by a variety of conditions. Although peptic ulcer disease (PUD) has not been emphasized as a common cause of abdominal symptoms in CF, the risk for the development of PUD may be increased because of abnormal physiology. Contrast radiography appears to be an especially inaccurate method to document PUD in CF because the duodenal mucosa typically appears nodular and distorted with poor definition of the mucosal folds. These findings may obscure or mimic PUD. The first endoscopic diagnosis of PUD is reported in a CF patient. Based on this case and a review of the literature, endoscopy is the procedure of choice for evaluation of a CF patient who is suspected of having PUD.
腹痛在囊性纤维化（CF）患者中很常见，可能由多种情况引起。尽管消化性溃疡病（PUD）尚未被视为CF患者腹部症状的常见原因，但由于生理异常，PUD的发病风险可能会增加。对比造影似乎是诊断CF患者PUD的一种特别不准确的方法，因为十二指肠黏膜通常呈结节状且扭曲，黏膜皱襞的清晰度较差。这些表现可能会掩盖或模拟PUD。本文报道了首例CF患者的PUD内镜诊断。基于该病例及文献回顾，对于疑似患有PUD的CF患者，内镜检查是首选的评估方法。
