Nature Dental Clinic, Puli Township, Nantou 404, Taiwan.
Department of Family Medicine, Dalin Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, No. 2, Minsheng Road, Dalin, Chiayi 622, Taiwan.
Medicina (Kaunas). 2023 Feb 27;59(3):471. doi: 10.3390/medicina59030471.
: Heart rate variability (HRV) analysis is a noninvasive method used to examine autonomic system function, and the clinical applications of HRV analysis have been well documented. The aim of this study is to investigate the association between HRV and the apnea-hypopnea index (AHI) in patients referred for polysomnography (PSG) for obstructive sleep apnea (OSA) diagnosis. : Patients underwent whole-night PSG. Data on nocturnal HRV and AHI were analyzed. We determined the correlation of time- and frequency-domain parameters of HRV with the AHI. : A total of 62 participants (50 men and 12 women) were enrolled. The mean age, body mass index (BMI), neck circumference, and AHI score of the patients were 44.4 ± 11.5 years, 28.7 ± 5.2, 40.2 ± 4.8 cm, and 32.1 ± 27.0, respectively. The log root mean square of successive differences between normal heartbeats (RMSSD) were negatively correlated with BMI ( = 0.034) and neck circumference ( = 0.003). The log absolute power of the low-frequency band over high-frequency band (LF/HF) ratio was positively correlated with the AHI ( = 0.006). A higher log LF/HF power ratio ( = 5.01, = 0.029) and BMI ( = 2.20, < 0.001) were associated with a higher AHI value in multiple linear regression analysis. : A higher log LF/HF power ratio and BMI were positively and significantly associated with the AHI during whole-night PSG in adult patients.
心率变异性（HRV）分析是一种用于检查自主神经系统功能的非侵入性方法，其临床应用已有充分记录。本研究旨在探讨 HRV 与阻塞性睡眠呼吸暂停（OSA）诊断性多导睡眠图（PSG）患者的呼吸暂停低通气指数（AHI）之间的关系。
患者接受整夜 PSG。分析夜间 HRV 和 AHI 数据。我们确定了 HRV 的时频域参数与 AHI 的相关性。
共纳入 62 名患者（50 名男性和 12 名女性）。患者的平均年龄、体重指数（BMI）、颈围和 AHI 评分分别为 44.4 ± 11.5 岁、28.7 ± 5.2、40.2 ± 4.8 cm 和 32.1 ± 27.0。正常心跳之间的对数均方根差（RMSSD）呈负相关与 BMI（ = 0.034）和颈围（ = 0.003）。低频带绝对功率与高频带（LF/HF）比值的对数呈正相关与 AHI（ = 0.006）。在多元线性回归分析中，较高的 LF/HF 功率比的对数（ = 5.01， = 0.029）和 BMI（ = 2.20， < 0.001）与 AHI 值较高相关。
在成年患者整夜 PSG 期间，较高的 LF/HF 功率比和 BMI 与 AHI 呈正相关且显著相关。
