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一项针对急诊科肾绞痛诊断性检查的影像学策略的真实世界成本效益研究。

A Real-World Cost-Effectiveness Study Evaluating Imaging Strategies for the Diagnostic Workup of Renal Colic in the Emergency Department.

机构信息

Emergency Department, Hôpitaux Universitaires de Strasbourg, 1 Place de L'hôpital, CHRU of Strasbourg, 67091 Strasbourg, France.

ICUBE UMR 7357 CNRS, Équipe IMAGeS, 300 Bd Sébastien Brant, 67400 Illkirch-Graffenstaden, France.

出版信息

Medicina (Kaunas). 2023 Feb 28;59(3):475. doi: 10.3390/medicina59030475.

Abstract

Both non-contrast Computed Tomography (CT) and ultrasound (US) are used for the diagnosis of renal colic in the emergency department (ED). Although US reduces radiation exposure, its diagnostic accuracy is inferior to that of CT. In this context, data regarding the cost and organizational impact of these strategies represent essential elements in the choice of imaging; however, they remain poorly documented. The aim of this study was to compare the costs and effectiveness of diagnostic workup by US and CT for patients consulting with renal colic in the ED. We conducted a monocentric real-life retrospective study of patients consulting for a renal colic in an ED between 1 July 2018 and 31 December 2018. We estimated length of stay (LOS), total hospital costs at 60 days including ED, and initial and repeat admissions. Patients with initial US in the ED were compared to patients with initial CT using inverse probability weighting of the propensity score calculated from demographic variables, vital parameters, and clinical presentation. We calculated the incremental cost effectiveness ratio as the difference in costs by the difference in LOS. The variability of the results was assessed using non-parametric bootstrapping. In this study, of the 273 patients included, 67 were patients assessed with US and 206 with CT. The average costs were €1159 (SD 1987) and €956 (SD 1462) for US and CT, respectively, and the ED LOS was 8.9 [CI 95% 8.1; 9.4] and 8.7 [CI 95% 7.9; 9.9] hours for US and CT, respectively. CT was associated with a decreased LOS by 0.139 [CI 95% -1.1; 1.5] hours and was cost-saving, with a €199 [CI 95% -745; 285] reduction per patient. When imaging is required in the ED for suspected renal colic as recommended, there is real-life evidence that CT is a cost-effective strategy compared to US, reducing costs and LOS in the ED.

摘要

在急诊科(ED),非对比计算机断层扫描(CT)和超声(US)均用于肾绞痛的诊断。虽然 US 减少了辐射暴露,但它的诊断准确性不如 CT。在这种情况下,这些策略的成本和组织影响的数据是选择影像学的重要因素,但它们的记录仍不完善。本研究旨在比较 US 和 CT 对 ED 肾绞痛患者的诊断检查的成本和效果。

我们进行了一项单中心真实回顾性研究,纳入 2018 年 7 月 1 日至 12 月 31 日在 ED 就诊的肾绞痛患者。我们估计了住院时间(LOS)、60 天内 ED 和初始及重复入院的总住院费用。将 ED 中初始 US 的患者与初始 CT 的患者进行比较,使用从人口统计学变量、生命体征和临床表现计算的倾向评分的逆概率加权。我们计算了增量成本效果比,即 LOS 差异引起的成本差异。使用非参数自举法评估结果的变异性。

在这项研究中,273 名患者中,67 名患者接受了 US 检查,206 名患者接受了 CT 检查。US 和 CT 的平均费用分别为 1159 欧元(SD 1987)和 956 欧元(SD 1462),ED LOS 分别为 8.9 [CI 95% 8.1; 9.4]和 8.7 [CI 95% 7.9; 9.9]小时。CT 检查可使 LOS 缩短 0.139 [CI 95% -1.1; 1.5]小时,且节省成本,每位患者可节省 199 欧元(CI 95% -745;285)。

当根据建议在 ED 对疑似肾绞痛进行影像学检查时,真实世界的证据表明,与 US 相比,CT 是一种具有成本效益的策略,可降低 ED 的成本和 LOS。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/80cc/10058030/a5cb0f1491c7/medicina-59-00475-g001.jpg

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