Department of Urology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki 852-8501, Japan.
Medicina (Kaunas). 2023 Feb 28;59(3):476. doi: 10.3390/medicina59030476.
: To examine the relationship between the presence of earlobe crease (EC) and overactive bladder (OAB). : The earlobes of the participants were examined macroscopically. ECs were further divided into four groups (grades 0-3) according to severity. Subjective symptoms were assessed using the OAB symptom score (OABSS), and objective findings were assessed using uroflowmetry. The relationship between these findings and the presence or absence and severity of EC was also examined. A score of ≥2 points on OABSS question 3 (urinary urgency), with a total score of ≥3 points, indicated OAB. : We analyzed 246 participants, including 120 (48.8%) in the EC group and 126 (51.2%) in the non-EC (N-EC) group. On the OABSS, the EC group scored higher than the N-EC group for all questions and for the total score. The total OABSS of EC grade 3 was the highest of all groups. A total of 115 (95.8%) patients in the EC group (100% in grade 3) and 69 (54.8%) in the N-EC group met the OAB criteria ( < 0.001). The voided volume and maximum flow rate of the EC group were significantly lower than those of the N-EC group (both < 0.001). The post-void residual urine volume in the EC group was significantly higher than that in the N-EC group ( = 0.029). Multivariate analysis revealed that EC was an independent risk factor for OAB (odds ratio, 8.15; 95% confidence interval, 2.84-24.75; < 0.001). : The presence of an earlobe crease may be a predictive marker for OAB.
: 目的：探讨耳垂折痕（EC）与膀胱过度活动症（OAB）之间的关系。
: 方法：对参与者的耳垂进行了宏观检查。EC 进一步根据严重程度分为四级（0-3 级）。使用 OAB 症状评分（OABSS）评估主观症状，使用尿流率测定评估客观发现。还检查了这些发现与 EC 的存在、严重程度之间的关系。OABSS 问题 3（尿急）得分≥2 分，总分≥3 分，表明存在 OAB。
: 结果：我们分析了 246 名参与者，包括 120 名（48.8%）EC 组和 126 名（51.2%）非 EC（N-EC）组。在 OABSS 上，EC 组在所有问题和总分上的得分均高于 N-EC 组。EC 3 级的总 OABSS 是所有组中最高的。EC 组中共有 115 名（95.8%）（100%为 3 级）和 N-EC 组中 69 名（54.8%）患者符合 OAB 标准（<0.001）。EC 组的排尿量和最大流量明显低于 N-EC 组（均<0.001）。EC 组的剩余尿量明显高于 N-EC 组（=0.029）。多变量分析显示，EC 是 OAB 的独立危险因素（比值比，8.15；95%置信区间，2.84-24.75；<0.001）。
: 结论：耳垂折痕的存在可能是 OAB 的预测指标。
