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肉瘤转移疾病的消融技术:当前作用和临床应用。

Ablative Techniques for Sarcoma Metastatic Disease: Current Role and Clinical Applications.

机构信息

2nd Department of Radiology, University General Hospital "ATTIKON", Medical School, National and Kapodistrian University of Athens, 12462 Athens, Greece.

出版信息

Medicina (Kaunas). 2023 Mar 1;59(3):485. doi: 10.3390/medicina59030485.

Abstract

Sarcomas are heterogenous mesenchymal neoplasms with more than 80 different histologic subtypes. Lung followed by liver and bone are the most common sites of sarcoma metastatic disease. Ablative techniques have been recently added as an additional alternative curative or palliative therapeutic tool in sarcoma metastatic disease. When compared to surgery, ablative techniques are less invasive therapies which can be performed even in non-surgical candidates and are related to decreased recovery time as well as preservation of the treated organ's long-term function. Literature data upon ablative techniques for sarcoma metastatic disease are quite heterogeneous and variable regarding the size and the number of the treated lesions and the different histologic subtypes of the original soft tissue or bone sarcoma. The present study focuses upon the current role of minimal invasive thermal ablative techniques for the management of metastatic sarcoma disease. The purpose of this review is to present the current minimally invasive ablative techniques in the treatment of metastatic soft tissue and bone sarcoma, including local control and survival rates.

摘要

肉瘤是一种具有 80 多种不同组织学亚型的异质性间叶肿瘤。肺、肝和骨是肉瘤转移疾病最常见的转移部位。消融技术最近被作为肉瘤转移疾病的另一种治疗选择,既可以作为根治性治疗方法,也可以作为姑息性治疗手段。与手术相比,消融技术是一种创伤更小的治疗方法,甚至可以在非手术患者中进行,并且与恢复时间缩短以及治疗器官的长期功能保存相关。关于肉瘤转移疾病的消融技术的文献数据差异很大,不同研究中消融治疗的病灶大小和数量以及原发软组织或骨肉瘤的不同组织学亚型均不相同。本研究重点介绍了微创热消融技术在治疗转移性肉瘤疾病中的当前作用。本综述的目的是介绍治疗转移性软组织和骨肉瘤的微创消融技术,包括局部控制率和生存率。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bbbe/10054887/0c91ec902491/medicina-59-00485-g001.jpg

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