Krawczak Felipe S, Binder Lina C, Gregori Fábio, Martins Thiago F, Pádua Gracielle T, Sponchiado Jonas, Melo Geruza L, Polo Gina, Labruna Marcelo B
Setor de Medicina Veterinária Preventiva, Departamento de Medicina Veterinária, Escola de Veterinária e Zootecnia, Universidade Federal de Goiás, Rod. Goiânia-Nova Veneza, km 8, Campus Samambaia, Goiânia 74690-900, GO, Brazil.
Departamento de Medicina Veterinária Preventiva e Saúde Animal, Faculdade de Medicina Veterinária e Zootecnia, Universidade de São Paulo, Av. Prof. Orlando Marques de Paiva, 87, Cidade Universitária, São Paulo 05508-270, SP, Brazil.
Pathogens. 2023 Mar 12;12(3):446. doi: 10.3390/pathogens12030446.
Spotted fever illness caused by the tick-borne pathogen has emerged in the Pampa biome in southern Brazil, where the tick is implicated as the main vector. Because domestic dogs are commonly parasitized by this canid is also a suitable sentinel for -associated spotted fever. Herein, we investigate rickettsial infection in ticks, domestic dogs and small mammals in a natural reserve of the Pampa biome in southern Brazil. The ticks and were collected from dogs. Molecular analyses of ticks did not detect ; however, at least 34% (21/61) of the ticks were infected by the non-pathogenic agent ' Rickettsia andeanae'. Serological analyses revealed that only 14% and 3% of 36 dogs and 34 small mammals, respectively, were exposed to rickettsial antigens. These results indicate that the study area is not endemic for rickettsiosis. We tabulated 10 studies that reported rickettsial infection in populations from South America. There was a strong negative correlation between the infection rates by and ' R. andeanae' in populations. We propose that high infection rates by ' R. andeanae' might promote the exclusion of from populations. The mechanisms for such exclusion are yet to be elucidated.
由蜱传播病原体引起的斑点热疾病已在巴西南部的潘帕生物群落中出现，在那里蜱被认为是主要传播媒介。由于家犬常被这种蜱寄生，所以这种犬科动物也是与相关斑点热有关的合适哨兵。在此，我们调查了巴西南部潘帕生物群落一个自然保护区内蜱、家犬和小型哺乳动物的立克次体感染情况。蜱和是从狗身上采集的。对蜱的分子分析未检测到；然而，至少34%（21/61）的蜱被非致病性立克次体“安第斯立克次体”感染。血清学分析显示，36只狗和34只小型哺乳动物中分别只有14%和3%接触过立克次体抗原。这些结果表明，研究区域并非立克次体病的地方流行区。我们列出了10项报告南美洲人群中立克次体感染情况的研究。人群中感染率与“安第斯立克次体”感染率之间存在很强的负相关。我们提出，“安第斯立克次体”的高感染率可能会促使其从人群中排除。这种排除的机制尚待阐明。
