Lieberoth Sofie, Kumar Sheetal, Brusgaard Klaus, Ousager Lillian B, Betz Regina C, Bygum Anette
Department of Dermatology and Allergy Centre, Odense University Hospital, Odense, Denmark;
Medical Faculty, University Hospital Bonn, Institute of Human Genetics, University of Bonn, Venusberg Campus 1, Bonn, Germany.
Skinmed. 2023 Mar 29;21(1):44-46. eCollection 2023.
A 1-year-old girl presented with porcelain white fingernails, accidentally discovered when she was referred for an infantile hemangioma consultation. The family reported that the nails had been milky white since birth and her father had similar white finger and toenails. The father remembered that additional family members on his side of the family presented with white nails; however, he could not provide exact information about the number of other relatives affected by this nail abnormality. The girl and her father were the only available family members with white nails presented for this study (Figure 1). The girl presented with leukonychia totalis on all fingernails only, while the father had this abnormality on all finger and toenails (Figure 2). We were not aware of any association with other diseases or features in this family, except hemangioma in the girl. (. 2023;21:44-46).
一名1岁女童因婴幼儿血管瘤会诊前来就诊时，意外发现其指甲呈瓷白色。家人报告称，自出生以来，她的指甲就是乳白色的，她的父亲也有类似的白色手指和脚趾甲。父亲记得，他家族中其他一些成员也有白色指甲；然而，他无法提供受这种指甲异常影响的其他亲属的确切人数。该女童和她的父亲是本研究中仅有的有白色指甲的家庭成员（图1）。该女童仅所有手指甲出现全白甲，而其父亲所有手指和脚趾甲均有这种异常（图2）。除了该女童患有血管瘤外，我们未发现这个家族中存在与其他疾病或特征的任何关联。（. 2023;21:44 - 46）
