Section of Midwifery Science, Institute for Health Sciences, University Hospital Tübingen, Hoppe-Seyler-Str. 9, 72076, Tübingen, Germany.
Department for Women's Health, University Hospital Tübingen, Calwerstr. 7, 72076, Tübingen, Germany.
Arch Gynecol Obstet. 2024 Jan;309(1):47-62. doi: 10.1007/s00404-023-06990-1. Epub 2023 Mar 29.
This narrative review was performed to evaluate the correct timing of umbilical cord clamping for term infants. It was intended to determine any advantages or disadvantages from early or delayed cord clamping for newborns, infants or mothers.
A systematic search on two databases was conducted using the PICO pattern to define a wide search. Out of 43 trials, 12 were included in this review. Three of the included studies are meta-analyses, nine are randomized controlled trials.
Early or delayed cord clamping was defined differently in all the included trials. However, there are many advantages from delayed cord clamping of at least > 60 s for newborns and infants up to 12 months of age. The trials showed no disadvantages for newborns or mothers from delayed cord clamping, except for a lightly increased risk of jaundice or the need for phototherapy.
Delayed umbilical cord clamping for term infants should be performed. Further research is needed to improve knowledge on physiological timing of umbilical cord clamping in term infants, which also leads to the same advantages as delayed cord clamping.
本叙述性评论旨在评估足月婴儿脐带结扎的正确时机。旨在确定新生儿、婴儿或母亲早期或延迟脐带结扎的任何优势或劣势。
使用 PICO 模式对两个数据库进行了系统搜索,以定义广泛的搜索。在 43 项试验中,有 12 项被纳入本综述。纳入的三项研究是荟萃分析,九项是随机对照试验。
所有纳入的试验中,早期或延迟脐带结扎的定义都不同。然而,对于新生儿和 12 个月大的婴儿,至少延迟脐带结扎 60 秒以上有许多优势。这些试验表明,延迟脐带结扎对新生儿或母亲没有不利影响,除了轻度增加黄疸风险或需要光疗的风险。
应在足月婴儿中实施延迟脐带结扎。需要进一步的研究来提高对足月婴儿脐带结扎生理时机的认识,这也能带来与延迟脐带结扎相同的优势。