Department of Pathology and Laboratory Medicine, University of California Los Angeles, David Geffen School of Medicine, Los Angeles, California.
Division of Infectious Diseases, University of California Los Angeles, David Geffen School of Medicine, Los Angeles, California.
Int J Infect Dis. 2023 Jul;132:1-3. doi: 10.1016/j.ijid.2023.03.039. Epub 2023 Mar 28.
Clustered outbreaks of multi-drug resistant (MDR) Shigella are on the rise among men who have sex with men (MSM). Identification of MDR sub-lineages is critical for clinical management and public health interventions. Here, we describe a novel MDR sub-lineage of Shigella flexneri isolated from an MSM patient without a travel history in Southern California. Detailed genomic characterization of this novel strain would serve as a reference to aid monitoring and future outbreak investigation of MDR Shigella among MSM.
多药耐药（MDR）志贺菌属的聚集性暴发在男男性行为者（MSM）中呈上升趋势。鉴定 MDR 亚谱系对于临床管理和公共卫生干预至关重要。在这里，我们描述了从加利福尼亚州南部的一名没有旅行史的 MSM 患者中分离出的新型福氏志贺菌 MDR 亚谱系。对这种新型菌株的详细基因组特征进行描述将作为参考，有助于监测和未来对 MSM 中 MDR 志贺菌的暴发进行调查。
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