Koshelev V B, Kondashevskaia M V, Stavskaia O N, Vasil'ev N B, Timkina M I
Fiziol Zh SSSR Im I M Sechenova. 1986 Feb;72(2):198-206.
A correlation was found between the initial relative thickness of vascular wall and the extent of vasoconstriction in response to standard stimulation of sympathetic strings. The distribution of vessels within the wall was comprised in mathematical model which estimated interrelationships among three variables: pressure perfusate expenditure and a conventional dose of vasoconstricting agent. The model revealed that intense vasoconstrictory responses entailed a decrease in the number of functioning vessels. When perfusing the rat hindlimbs with a constant expenditure in maximal vasoconstriction, the number of functioning microvessels decreased by 46 +/- 11.9%.
在血管壁的初始相对厚度与交感神经索标准刺激后血管收缩程度之间发现了一种相关性。血管壁内血管的分布被纳入一个数学模型，该模型估计了三个变量之间的相互关系：灌注压力、灌注液消耗量和常规剂量的血管收缩剂。该模型显示，强烈的血管收缩反应会导致功能正常的血管数量减少。当以最大血管收缩时的恒定灌注液消耗量灌注大鼠后肢时，功能正常的微血管数量减少了46±11.9%。
