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长期营养不良大鼠的空间线索利用:特定任务的学习缺陷。

Spatial cue utilization in chronically malnourished rats: task-specific learning deficits.

作者信息

Goodlett C R, Valentino M L, Morgane P J, Resnick O

出版信息

Dev Psychobiol. 1986 Jan;19(1):1-15. doi: 10.1002/dev.420190102.

DOI:10.1002/dev.420190102
PMID:3699248
Abstract

Rats whose mothers were maintained on either a 25% casein diet or an 8% casein diet and who were provided the same diet after weaning were tested on delayed spatial alternation or on one of a series of spatial localization problems using the Morris maze (Morris, 1981). Malnourished rats demonstrated perseverative deficits in the form of strings of consecutive errors on the delayed spatial alternation. Performance in the Morris maze indicated spatial localization ability and spatial memory processes were not impaired by chronic malnutrition in rats. The data suggest that complex processing of spatial information that includes flexible use of place cues over short intervals is impaired by malnutrition, while spatial localization per se and spatial mapping are not affected.

摘要

其母亲分别维持在25%酪蛋白饮食或8%酪蛋白饮食,断奶后给予相同饮食的大鼠,使用莫里斯水迷宫(Morris,1981)在延迟空间交替或一系列空间定位问题中的一项上进行测试。营养不良的大鼠在延迟空间交替中表现出以一连串连续错误形式出现的持续性缺陷。莫里斯水迷宫中的表现表明,慢性营养不良并未损害大鼠的空间定位能力和空间记忆过程。数据表明,营养不良会损害包括在短时间间隔内灵活使用位置线索的空间信息的复杂处理,而空间定位本身和空间映射则不受影响。

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