Kindratt Tiffany Billmeier, Ajrouch Kristine J, Zahodne Laura B, Dallo Florence J
University of Texas at Arlington.
U-M: University of Michigan.
Res Sq. 2023 Mar 24:rs.3.rs-1983254. doi: 10.21203/rs.3.rs-1983254/v1.
Background ADRD underdiagnosis among minority populations is well-established and known to be more prevalent among women. Yet, it remains unclear if these patterns exist among Middle Eastern and North African (MENA) adults. We estimated ADRD underdiagnosis among MENA and other US- and foreign-born non-Hispanic Whites and compared sex-stratified results. Methods We linked 2000-2017 National Health Interview Survey and 2001-2018 Medical Expenditure Panel Survey data (ages > = 65 years, n = 23,981). Undiagnosed ADRD was suspected if participants reported cognitive limitations without corresponding ADRD diagnosis. Results Undiagnosed ADRD was highest among MENA adults (15.8%) compared to non-Hispanic Whites (US-born = 8.1%; foreign-born = 11.8%). MENA women had 2.52 times greater odds (95% CI = 1.31-4.84) of undiagnosed ADRD compared to US-born White women after adjusting for risk factors. Discussion This study contributes the first national estimates of undiagnosed ADRD among MENA adults. Continued research is needed to facilitate policy changes that more comprehensively address health disparities and related resource allocation.
在少数族裔人群中，神经退行性疾病（ADRD）的诊断不足情况已得到充分证实，且已知在女性中更为普遍。然而，目前尚不清楚这些模式是否存在于中东和北非（MENA）成年人中。我们估计了中东和北非地区以及其他在美国出生和外国出生的非西班牙裔白人中ADRD的诊断不足情况，并比较了按性别分层的结果。方法：我们将2000 - 2017年国家健康访谈调查和2001 - 2018年医疗支出面板调查数据（年龄≥65岁，n = 23,981）进行了关联。如果参与者报告有认知障碍但没有相应的ADRD诊断，则怀疑为未确诊的ADRD。结果：与非西班牙裔白人（美国出生的 = 8.1%；外国出生的 = 11.8%）相比，中东和北非地区成年人中未确诊的ADRD比例最高（15.8%）。在调整风险因素后，与美国出生的白人女性相比，中东和北非地区女性未确诊ADRD的几率高2.52倍（95%置信区间 = 1.31 - 4.84）。讨论：本研究首次对中东和北非地区成年人中未确诊的ADRD进行了全国性估计。需要继续开展研究，以推动政策变革，更全面地解决健康差距和相关资源分配问题。
