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大流行期间丁丙诺啡治疗的远程医疗灵活性:美国扩大阿片类药物使用障碍护理的证据综合及政策影响

Pandemic telehealth flexibilities for buprenorphine treatment: A synthesis of evidence and policy implications for expanding opioid use disorder care in the U.S.

作者信息

Krawczyk Noa, Rivera Bianca D, King Carla, Dooling Bridget C E

机构信息

Center for Opioid Epidemiology and Policy (COEP), Department of Population Health, NYU Grossman School of Medicine, New York NY.

Regulatory Studies Center, The George Washington University, Washington, D.C.

出版信息

medRxiv. 2023 Mar 17:2023.03.16.23287373. doi: 10.1101/2023.03.16.23287373.

DOI:10.1101/2023.03.16.23287373
PMID:36993696
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10055597/
Abstract

Buprenorphine is a highly effective treatment for opioid use disorder and a critical tool for addressing the worsening U.S. overdose crisis. However, multiple barriers to treatment - including stringent federal regulations - have historically made this medication hard to reach for many who need it. In 2020, under the COVID-19 Public Health Emergency, federal regulators substantially changed access to buprenorphine by allowing prescribers to initiate patients on buprenorphine via telehealth without first evaluating them in person. As the Public Health Emergency is set to expire in May of 2023, Congress and federal agencies can leverage extensive evidence from studies conducted during the wake of the pandemic to make evidence-based decisions on the regulation of buprenorphine going forward. To aid policy makers, this review synthesizes and interprets peer-reviewed research on the effect of buprenorphine flexibilities on uptake and implementation of telehealth, and its impact on OUD patient and prescriber experiences, access to treatment and health outcomes. Overall, our review finds that many prescribers and patients took advantage of telehealth, including the audio-only option, with a wide range of benefits and few downsides. As a result, federal regulators-including agencies and Congress-should continue non-restricted use of telehealth for buprenorphine initiation.

摘要

丁丙诺啡是治疗阿片类物质使用障碍的一种高效药物,也是应对美国日益严重的药物过量危机的关键工具。然而,包括严格的联邦法规在内的多种治疗障碍,长期以来使得许多有需求的人难以获得这种药物。2020年,在新冠疫情公共卫生紧急状态下,联邦监管机构大幅改变了丁丙诺啡的获取方式,允许开处方者通过远程医疗为患者启动丁丙诺啡治疗,而无需先进行面对面评估。由于公共卫生紧急状态将于2023年5月到期,国会和联邦机构可以利用疫情期间开展的研究得出的大量证据,对丁丙诺啡未来的监管做出基于证据的决策。为帮助政策制定者,本综述综合并解读了同行评议研究,这些研究涉及丁丙诺啡灵活性对远程医疗的采用和实施的影响,及其对阿片类物质使用障碍患者和开处方者体验、治疗可及性和健康结果的影响。总体而言,我们的综述发现,许多开处方者和患者利用了远程医疗,包括仅音频选项,带来了广泛的益处且弊端很少。因此,包括各机构和国会在内的联邦监管机构应继续无限制地使用远程医疗来启动丁丙诺啡治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3a37/10055597/9e633aeed2f5/nihpp-2023.03.16.23287373v1-f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3a37/10055597/9e633aeed2f5/nihpp-2023.03.16.23287373v1-f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3a37/10055597/9e633aeed2f5/nihpp-2023.03.16.23287373v1-f0001.jpg

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