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苏格兰精神药物处方与自杀率之间的关联:人口研究

Association between psychotropic drug prescription and suicide rates in Scotland: population study.

作者信息

Moore Fhionna R, Macleod Mairi, Harley Trevor A

机构信息

Institute of Health and Wellbeing, School of Medical, Veterinary, and Life Sciences, University of Glasgow, UK.

School of Psychology, University of Dundee, UK.

出版信息

BJPsych Bull. 2023 Apr;47(2):68-70. doi: 10.1192/bjb.2021.88.

DOI:10.1192/bjb.2021.88
PMID:36994682
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10063996/
Abstract

AIMS AND METHOD

Rates of prescriptions of antidepressants and suicide are inversely correlated at an epidemiological level. Less attention has been paid to relationships between other drugs used in mental health and suicide rates. Here we tested relationships between prescriptions of anxiolytics and antipsychotics and suicide rates in Scotland.

RESULTS

Suicide rates were inversely correlated with prescriptions of antidepressants and antipsychotics over 14 years (2004-2018), and positively with prescriptions of anxiolytics.

CLINICAL IMPLICATIONS

This illustrates the role of medications used in mental health in suicide prevention, and highlights the importance of identifying causal mechanisms that link anxiolytics with suicide.

摘要

目的与方法

在流行病学层面,抗抑郁药的处方率与自杀率呈负相关。人们较少关注心理健康领域使用的其他药物与自杀率之间的关系。在此,我们测试了苏格兰地区抗焦虑药和抗精神病药的处方与自杀率之间的关系。

结果

在14年(2004 - 2018年)期间,自杀率与抗抑郁药和抗精神病药的处方呈负相关,与抗焦虑药的处方呈正相关。

临床意义

这说明了心理健康用药在预防自杀中的作用,并强调了确定抗焦虑药与自杀之间因果机制的重要性。