• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

剖宫产术后镇痛——有哪些新进展?

Analgesia after cesarean section - what is new?

机构信息

Department of Anesthesiology and Intensive Care, Klinikum rechts der Isar, Technical University of Munich.

MVZ Perioperative Medicine Munich.

出版信息

Curr Opin Anaesthesiol. 2023 Jun 1;36(3):288-292. doi: 10.1097/ACO.0000000000001259. Epub 2023 Mar 1.

DOI:10.1097/ACO.0000000000001259
PMID:36994740
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10609703/
Abstract

PURPOSE OF REVIEW

Cesarean section is the most frequent surgical intervention, and pain following cesarean delivery unfortunately remains a common issue. The purpose of this article is to highlight the most effective and efficient options for postcesarean analgesia and to summarize current guidelines.

RECENT FINDINGS

The most effective form of postoperative analgesia is through neuraxial morphine. With adequate dosing, clinically relevant respiratory depression is extremely rare. It is important to identify women with increased risk of respiratory depression, as they might require more intensive postoperative monitoring. If neuraxial morphine cannot be used, abdominal wall block or surgical wound infiltration are very valuable alternatives. A multimodal regimen with intraoperative intravenous dexamethasone, fixed doses of paracetamol/acetaminophen, and nonsteroidal anti-inflammatory drugs reduce postcesarean opioid use. As the use of postoperative lumbar epidural analgesia impairs mobilization, double epidural catheters with lower thoracic epidural analgesia are a possible alternative.

SUMMARY

Adequate analgesia following cesarean delivery is still underused. Simple measures, such as multimodal analgesia regimens should be standardized according to institutional circumstances and defined as part of a treatment plan. Neuraxial morphine should be used whenever possible. If it cannot be used, abdominal wall blocks or surgical wound infiltration are good alternatives.

摘要

目的综述

剖宫产术是最常见的手术干预措施,但剖宫产术后疼痛仍然是一个常见问题。本文旨在强调剖宫产术后镇痛的最有效和最有效的选择,并总结当前的指南。

最新发现

术后最有效的镇痛形式是通过鞘内吗啡。在适当的剂量下,临床相关的呼吸抑制极为罕见。重要的是要识别出有呼吸抑制风险增加的妇女,因为她们可能需要更密集的术后监测。如果不能使用鞘内吗啡,腹壁阻滞或手术切口浸润是非常有价值的替代方法。术中静脉给予地塞米松、固定剂量的扑热息痛/对乙酰氨基酚和非甾体抗炎药的多模式方案可减少剖宫产术后阿片类药物的使用。由于术后腰椎硬膜外镇痛会影响活动,因此下胸段硬膜外镇痛的双硬膜外导管可能是一种替代方法。

总结

剖宫产术后充分的镇痛仍未得到充分利用。根据机构情况,应将多模式镇痛方案等简单措施标准化,并将其定义为治疗计划的一部分。只要有可能,就应使用鞘内吗啡。如果不能使用,腹壁阻滞或手术切口浸润是很好的替代方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ea6b/10609703/fdfc18763445/coana-36-288-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ea6b/10609703/fdfc18763445/coana-36-288-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ea6b/10609703/fdfc18763445/coana-36-288-g001.jpg

相似文献

1
Analgesia after cesarean section - what is new?剖宫产术后镇痛——有哪些新进展?
Curr Opin Anaesthesiol. 2023 Jun 1;36(3):288-292. doi: 10.1097/ACO.0000000000001259. Epub 2023 Mar 1.
2
Continuous local bupivacaine wound infusion with neuraxial morphine reduces opioid consumption after cesarean delivery.剖宫产术后持续局部伤口输注布比卡因联合蛛网膜下腔吗啡可减少阿片类药物的用量。
J Matern Fetal Neonatal Med. 2019 Dec;32(23):3895-3902. doi: 10.1080/14767058.2018.1474872. Epub 2018 May 30.
3
Analgesia After Cesarean Delivery in the United States 2008-2018: A Retrospective Cohort Study.2008 - 2018年美国剖宫产术后镇痛:一项回顾性队列研究。
Anesth Analg. 2021 Dec 1;133(6):1550-1558. doi: 10.1213/ANE.0000000000005587.
4
Ropivacaine continuous wound infusion versus epidural morphine for postoperative analgesia after cesarean delivery: a randomized controlled trial.罗哌卡因持续切口灌注与硬膜外吗啡用于剖宫产术后镇痛的随机对照试验。
Anesth Analg. 2012 Jan;114(1):179-85. doi: 10.1213/ANE.0b013e3182368e87. Epub 2011 Oct 24.
5
Neuraxial opioids for post-cesarean delivery analgesia: can hydromorphone replace morphine? A retrospective study.用于剖宫产术后镇痛的椎管内阿片类药物:氢吗啡酮能否替代吗啡?一项回顾性研究。
Int J Obstet Anesth. 2017 May;30:16-22. doi: 10.1016/j.ijoa.2016.12.008. Epub 2016 Dec 30.
6
Society for Obstetric Anesthesia and Perinatology Consensus Statement: Monitoring Recommendations for Prevention and Detection of Respiratory Depression Associated With Administration of Neuraxial Morphine for Cesarean Delivery Analgesia.产科麻醉与围产医学学会共识声明:椎管内吗啡用于剖宫产镇痛时预防和发现与呼吸抑制相关的监测推荐。
Anesth Analg. 2019 Aug;129(2):458-474. doi: 10.1213/ANE.0000000000004195.
7
Postcesarean delivery analgesia.剖宫产术后镇痛
Best Pract Res Clin Anaesthesiol. 2017 Mar;31(1):69-79. doi: 10.1016/j.bpa.2017.01.003. Epub 2017 Jan 12.
8
Continuous Ropivacaine Subfascial Wound Infusion Compared With Intrathecal Morphine for Postcesarean Analgesia: A Prospective, Randomized Controlled, Double-Blind Study.连续罗哌卡因筋膜下伤口输注与鞘内注射吗啡用于剖宫产术后镇痛的比较:一项前瞻性、随机对照、双盲研究。
Anesth Analg. 2017 Sep;125(3):907-912. doi: 10.1213/ANE.0000000000001892.
9
The efficacy of 2 doses of epidural morphine for postcesarean delivery analgesia: a randomized noninferiority trial.硬膜外吗啡 2 剂用于剖宫产术后镇痛的效果:一项随机非劣效性试验。
Anesth Analg. 2013 Sep;117(3):677-685. doi: 10.1213/ANE.0b013e31829cfd21. Epub 2013 Aug 6.
10
Cesarean analgesia using levobupivacaine continuous wound infiltration: a randomized trial.左旋布比卡因持续伤口浸润用于剖宫产镇痛:一项随机试验。
Eur J Obstet Gynecol Reprod Biol. 2015 Nov;194:125-30. doi: 10.1016/j.ejogrb.2015.08.023. Epub 2015 Aug 25.

引用本文的文献

1
Association of preoperative anxiety and depression with quality of recovery after caesarean delivery: a prospective observational study.剖宫产术后术前焦虑和抑郁与恢复质量的关联:一项前瞻性观察研究。
JA Clin Rep. 2025 Mar 29;11(1):19. doi: 10.1186/s40981-025-00782-z.
2
Effect of Dexmedetomidine on the ED and ED of Sufentanil in Patient-Controlled Intravenous Analgesia After Cesarean Section: A Randomized, Controlled, Double-Blind Trial.右美托咪定对剖宫产术后患者自控静脉镇痛中舒芬太尼起效时间和作用持续时间的影响:一项随机、对照、双盲试验
Drug Des Devel Ther. 2025 Jan 9;19:129-140. doi: 10.2147/DDDT.S494162. eCollection 2025.
3

本文引用的文献

1
Review of Postoperative Respiratory Depression: From Recovery Room to General Care Unit.术后呼吸抑制的综述:从恢复室到普通护理单元
Anesthesiology. 2022 Dec 1;137(6):735-741. doi: 10.1097/ALN.0000000000004391.
2
Evaluation of breastfeeding success and self-efficacy in mothers giving birth via vaginal delivery or cesarean section: a cross-sectional study.经阴道分娩或剖宫产的母亲母乳喂养成功率及自我效能的评估:一项横断面研究
Women Health. 2022 Oct-Dec;62(9-10):788-798. doi: 10.1080/03630242.2022.2146832. Epub 2022 Nov 20.
3
Efficacy of Single Wound Infiltration With Bupivacaine and Adrenaline During Cesarean Delivery for Reduction of Postoperative Pain: A Randomized Clinical Trial.
Refining post-cesarean delivery pain management.
优化剖宫产术后疼痛管理。
Proc (Bayl Univ Med Cent). 2024 Nov 19;38(1):5-6. doi: 10.1080/08998280.2024.2426411. eCollection 2025.
4
Pharmacologic Analgesia for Cesarean Section: An Update in 2024.剖宫产术的药物镇痛:2024 年更新。
Curr Pain Headache Rep. 2024 Oct;28(10):985-998. doi: 10.1007/s11916-024-01278-8. Epub 2024 Jul 1.
剖宫产术中单次浸润布比卡因和肾上腺素减轻术后疼痛的效果:一项随机临床试验。
JAMA Netw Open. 2022 Nov 1;5(11):e2242203. doi: 10.1001/jamanetworkopen.2022.42203.
4
Risk factors for postpartum depression in women undergoing elective cesarean section: A prospective cohort study.择期剖宫产女性产后抑郁的危险因素:一项前瞻性队列研究。
Front Med (Lausanne). 2022 Sep 28;9:1001855. doi: 10.3389/fmed.2022.1001855. eCollection 2022.
5
Respiratory depression after administration of single-dose neuraxial morphine for post-cesarean delivery analgesia: a retrospective cohort study.单次鞘内注射吗啡用于剖宫产术后镇痛后呼吸抑制:一项回顾性队列研究。
Int J Obstet Anesth. 2022 Nov;52:103592. doi: 10.1016/j.ijoa.2022.103592. Epub 2022 Aug 24.
6
Effectiveness of early essential newborn care on breastfeeding and maternal outcomes: a nonrandomized controlled study.早期基本新生儿护理对母乳喂养和产妇结局的效果:一项非随机对照研究。
BMC Pregnancy Childbirth. 2022 Sep 14;22(1):707. doi: 10.1186/s12884-022-05037-8.
7
Analgesic effect of ultrasound-guided erector spinae plane block (espb) in general anesthesia for cesarean section: a randomized controlled trial.超声引导竖脊肌平面阻滞(ESP 阻滞)在剖宫产全身麻醉中的镇痛效果:一项随机对照试验。
BMC Anesthesiol. 2022 Aug 2;22(1):244. doi: 10.1186/s12871-022-01781-8.
8
Postoperative Analgesic Effectiveness of Peripheral Nerve Blocks in Cesarean Delivery: A Systematic Review and Network Meta-Analysis.剖宫产术中周围神经阻滞的术后镇痛效果:一项系统评价和网状Meta分析
J Pers Med. 2022 Apr 14;12(4):634. doi: 10.3390/jpm12040634.
9
The analgesic efficacy of intravenous dexamethasone for post-caesarean pain: A systematic review with meta-analysis and trial sequential analysis.静脉注射地塞米松治疗剖宫产术后疼痛的疗效:系统评价、荟萃分析和试验序贯分析。
Eur J Anaesthesiol. 2022 Jun 1;39(6):498-510. doi: 10.1097/EJA.0000000000001626. Epub 2021 Nov 11.
10
Factors associated with infant formula supplementation in Brazilian hospitals: a cross-sectional study.与巴西医院婴儿配方奶粉补充相关的因素:一项横断面研究。
J Pediatr (Rio J). 2022 Sep-Oct;98(5):463-470. doi: 10.1016/j.jped.2021.12.009. Epub 2022 Feb 25.