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剖宫产术后镇痛——有哪些新进展?

Analgesia after cesarean section - what is new?

机构信息

Department of Anesthesiology and Intensive Care, Klinikum rechts der Isar, Technical University of Munich.

MVZ Perioperative Medicine Munich.

出版信息

Curr Opin Anaesthesiol. 2023 Jun 1;36(3):288-292. doi: 10.1097/ACO.0000000000001259. Epub 2023 Mar 1.

Abstract

PURPOSE OF REVIEW

Cesarean section is the most frequent surgical intervention, and pain following cesarean delivery unfortunately remains a common issue. The purpose of this article is to highlight the most effective and efficient options for postcesarean analgesia and to summarize current guidelines.

RECENT FINDINGS

The most effective form of postoperative analgesia is through neuraxial morphine. With adequate dosing, clinically relevant respiratory depression is extremely rare. It is important to identify women with increased risk of respiratory depression, as they might require more intensive postoperative monitoring. If neuraxial morphine cannot be used, abdominal wall block or surgical wound infiltration are very valuable alternatives. A multimodal regimen with intraoperative intravenous dexamethasone, fixed doses of paracetamol/acetaminophen, and nonsteroidal anti-inflammatory drugs reduce postcesarean opioid use. As the use of postoperative lumbar epidural analgesia impairs mobilization, double epidural catheters with lower thoracic epidural analgesia are a possible alternative.

SUMMARY

Adequate analgesia following cesarean delivery is still underused. Simple measures, such as multimodal analgesia regimens should be standardized according to institutional circumstances and defined as part of a treatment plan. Neuraxial morphine should be used whenever possible. If it cannot be used, abdominal wall blocks or surgical wound infiltration are good alternatives.

摘要

目的综述

剖宫产术是最常见的手术干预措施,但剖宫产术后疼痛仍然是一个常见问题。本文旨在强调剖宫产术后镇痛的最有效和最有效的选择,并总结当前的指南。

最新发现

术后最有效的镇痛形式是通过鞘内吗啡。在适当的剂量下,临床相关的呼吸抑制极为罕见。重要的是要识别出有呼吸抑制风险增加的妇女,因为她们可能需要更密集的术后监测。如果不能使用鞘内吗啡,腹壁阻滞或手术切口浸润是非常有价值的替代方法。术中静脉给予地塞米松、固定剂量的扑热息痛/对乙酰氨基酚和非甾体抗炎药的多模式方案可减少剖宫产术后阿片类药物的使用。由于术后腰椎硬膜外镇痛会影响活动,因此下胸段硬膜外镇痛的双硬膜外导管可能是一种替代方法。

总结

剖宫产术后充分的镇痛仍未得到充分利用。根据机构情况,应将多模式镇痛方案等简单措施标准化,并将其定义为治疗计划的一部分。只要有可能,就应使用鞘内吗啡。如果不能使用,腹壁阻滞或手术切口浸润是很好的替代方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ea6b/10609703/fdfc18763445/coana-36-288-g001.jpg

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