Vagelos College of Physicians and Surgeons, Columbia University, New York, New York, USA.
Department of Surgery, Division of Surgical Oncology, Columbia University Irving Medical Center, New York, New York, USA.
J Surg Oncol. 2023 Jul;128(1):87-96. doi: 10.1002/jso.27258. Epub 2023 Mar 31.
Dermatofibrosarcoma protuberans (DFSP) is an uncommon, locally aggressive cutaneous malignancy. Complete resection is the primary treatment but there is debate over the optimal method. Wide local excision was traditionally the standard of care; however, National Comprehensive Cancer Network guidelines now recommend Mohs micrographic surgery as the preferred approach. Medical therapy with imatinib can be used in advanced or unresectable disease. This review will discuss the current management of DFSP, focusing on optimal surgical approach.
隆突性皮肤纤维肉瘤（DFSP）是一种罕见的局部侵袭性皮肤恶性肿瘤。完全切除是主要的治疗方法，但对于最佳方法仍存在争议。传统上广泛局部切除是标准治疗方法；然而，美国国家综合癌症网络指南现在建议 Mohs 显微外科手术作为首选方法。对于晚期或不可切除的疾病，可以使用伊马替尼进行药物治疗。本文将讨论 DFSP 的当前治疗方法，重点是最佳手术方法。
