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猫视网膜中星形胶质细胞的形态与分布。

Shape and distribution of astrocytes in the cat retina.

作者信息

Karschin A, Wässle H, Schnitzer J

出版信息

Invest Ophthalmol Vis Sci. 1986 May;27(5):828-31.

PMID:3700032
Abstract

Astrocytes in the adult cat retina were stained by immunocytochemical localization of glial fibrillary acidic protein (GFAP), a major constituent of the astrocytic intermediate filaments. Their density in whole mounted retinae showed a peak of about 2000 astrocytes/mm2 at the optic nerve head and dropped to approximately 200 astrocytes/mm2 in the far periphery. At the central area a prominent local minimum of astrocyte density was found. The shape of astrocytes changed from a stellate form in the outermost retinal periphery to an elongated form in the central part of the retina with the majority of astroglial processes aligned in parallel with the ganglion cell axons. Results in the cat retina suggest a close correlation between astrocytes and optic nerve fibers, the latter presumably being involved in the establishment of the astrocytic network.

摘要

通过对胶质纤维酸性蛋白(GFAP)进行免疫细胞化学定位,对成年猫视网膜中的星形胶质细胞进行了染色,GFAP是星形胶质细胞中间丝的主要成分。它们在整个视网膜标本中的密度在视神经乳头处显示出约2000个星形胶质细胞/平方毫米的峰值,并在最外周降至约200个星形胶质细胞/平方毫米。在中心区域发现星形胶质细胞密度有一个明显的局部最小值。星形胶质细胞的形状从视网膜最外周的星状形式变为视网膜中心部分的细长形式,大多数星形胶质细胞突起与神经节细胞轴突平行排列。猫视网膜的结果表明星形胶质细胞与视神经纤维之间存在密切相关性,后者可能参与了星形胶质细胞网络的建立。

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1
Shape and distribution of astrocytes in the cat retina.猫视网膜中星形胶质细胞的形态与分布。
Invest Ophthalmol Vis Sci. 1986 May;27(5):828-31.
2
Immunocytochemical studies on astroglia of the cat retina under normal and pathological conditions.正常及病理条件下猫视网膜星形胶质细胞的免疫细胞化学研究。
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Sustained Retinal Defocus Increases the Effect of Induced Myopia on the Retinal Astrocyte Template.持续视网膜离焦增加诱导性近视对视网膜星形胶质细胞模板的影响。
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Astrocytes and Müller Cell Alterations During Retinal Degeneration in a Transgenic Rat Model of Retinitis Pigmentosa.视网膜色素变性转基因大鼠模型视网膜变性过程中星形胶质细胞和米勒细胞的改变
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Comparative anatomy of the optic nerve head and inner retina in non-primate animal models used for glaucoma research.用于青光眼研究的非灵长类动物模型中视神经乳头和视网膜内层的比较解剖学。
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