Department of Social Psychiatry, the Affiliated Brain Hospital of Guangzhou Medical University (Guangzhou Huiai Hospital), Guangzhou, China.
Department of Social Psychiatry, the Affiliated Brain Hospital of Guangzhou Medical University (Guangzhou Huiai Hospital), Guangzhou, China.
Schizophr Res. 2023 May;255:182-188. doi: 10.1016/j.schres.2023.03.036. Epub 2023 Mar 28.
Although many studies have found an association between psychotic-like experiences (PLEs) and suicidal ideation (SI), the underlying psychological mechanisms have not been well established. Therefore, we conducted a longitudinal study in technical secondary school and college students to explore the role of fear-response to the COVID-19 and depression in the association between PLEs and SI in the context of the COVID-19 pandemic.
PLEs were assessed using the 15-item Positive Subscale of the Community Assessment of Psychic Experiences (CAPE-P15). Depression, fear, and SI were assessed using the Psychological Questionnaire for Public Health Emergency (PQPHE). PLEs were evaluated before the pandemic (T1), and fear, depression, and SI were measured during the pandemic (T2).
A total of 938 students completed both waves of the survey through electronic questionnaires. PLEs, fear, depression, and SI were all correlated with each other (all p < 0.01). T2 depression partly (58.2 %) mediated the relationship between T1 PLEs and T2 SI (b = 0.15, 95%CI = 0.10, 0.22). T2 Fear moderated the relationship between T1 PLEs and T2 depression (b = 0.05, 95%CI = 0.01, 0.09) and the relationship between T1 PLEs and T2 SI (b = 0.11, 95%CI = 0.06, 0.16).
PLEs are both directly and indirectly related to SI. Depression can result from PLEs and lead to the subsequent SI. Additionally, high levels of fear during the COVID-19 pandemic can aggravate the adverse impact of PLEs on mental health problems. These findings provide potential targets for future suicide prevention.
虽然许多研究已经发现类精神病体验（PLEs）与自杀意念（SI）之间存在关联，但潜在的心理机制尚未得到很好的确立。因此，我们在中等技术学校和大学学生中进行了一项纵向研究，以探索在 COVID-19 大流行背景下，对 COVID-19 的恐惧反应和抑郁在 PLEs 与 SI 之间关联中的作用。
使用 15 项社区心理体验评估量表（CAPE-P15）的阳性量表评估 PLEs。使用突发公共卫生事件心理问卷（PQPHE）评估抑郁、恐惧和 SI。在大流行前（T1）评估 PLEs，在大流行期间（T2）测量恐惧、抑郁和 SI。
共有 938 名学生通过电子问卷完成了两次调查。PLEs、恐惧、抑郁和 SI 之间均相互关联（均 p<0.01）。T2 抑郁部分（58.2%）中介了 T1 PLEs 与 T2 SI 之间的关系（b=0.15，95%CI=0.10，0.22）。T2 恐惧调节了 T1 PLEs 与 T2 抑郁（b=0.05，95%CI=0.01，0.09）和 T1 PLEs 与 T2 SI（b=0.11，95%CI=0.06，0.16）之间的关系。
PLEs 与 SI 直接和间接相关。抑郁可由 PLEs 引起，并导致随后的 SI。此外，在 COVID-19 大流行期间，恐惧程度较高会加剧 PLEs 对心理健康问题的不利影响。这些发现为未来的自杀预防提供了潜在的目标。
