测定依匹西林的间接分光光度法。
Indirect spectrophotometric method for determining epicillin.
作者信息
Núñez-Vergara L J, Roa A, Squella J A, González-Barbagelata R V
出版信息
J Assoc Off Anal Chem. 1986 Mar-Apr;69(2):188-90.
PMID:3700328
Abstract
A new UV spectrophotometric assay for determination of epicillin in capsules and plasma is reported. The method is based on the absorptivity of a degradation product obtained from the acidic hydrolysis of the antibiotic. The isolation, identification, individual capsule assays, composite assay, and recovery studies are described. Also, the proposed method is compared with a dc polarographic assay in plasma.
摘要
报道了一种用于测定胶囊和血浆中依匹西林的新型紫外分光光度法。该方法基于抗生素酸性水解所得降解产物的吸光率。描述了其分离、鉴定、单个胶囊测定、综合测定及回收率研究。此外，还将所提出的方法与血浆中的直流极谱法进行了比较。
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