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单光子发射计算机断层扫描的进展:硬件、软件和心肌血流储备。

Advances in Single-Photon Emission Computed Tomography: Hardware, Software, and Myocardial Flow Reserve.

机构信息

Division of Cardiology, University of Ottawa Heart Institute, 40 Ruskin Street, Ottawa, Ontario K1Y 4W7, Canada.

Division of Cardiology, University of Ottawa Heart Institute, 40 Ruskin Street, Ottawa, Ontario K1Y 4W7, Canada.

出版信息

Cardiol Clin. 2023 May;41(2):117-127. doi: 10.1016/j.ccl.2023.01.001. Epub 2023 Feb 25.

Abstract

The clinical presentation of coronary artery disease (CAD) has changed during the last 20 years with less ischemia on stress testing and more nonobstructive CAD on coronary angiography. Single-photon emission computed tomography (SPECT) myocardial perfusion imaging should include the measurement of myocardial flow reserve and assessment of coronary calcium for the diagnosis of nonobstructive CAD and coronary microvascular disease. SPECT/CT systems provide reliable attenuation correction for better specificity and low-dose CT for coronary calcium evaluation. SPECT MFR measurement is accurate, well validated, and repeatable.

摘要

在过去的 20 年中,冠状动脉疾病(CAD)的临床表现发生了变化,在应激试验中缺血减少,而在冠状动脉造影中无阻塞性 CAD 增多。单光子发射计算机断层扫描(SPECT)心肌灌注成像应包括心肌血流储备的测量和冠状动脉钙的评估,以诊断非阻塞性 CAD 和冠状动脉微血管疾病。SPECT/CT 系统为更好的特异性和低剂量 CT 冠状动脉钙评估提供可靠的衰减校正。SPECT MFR 测量准确、验证良好且可重复。

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