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自发性腰椎硬脊膜下脓肿:一例报告。

Spontaneous lumbar intraspinal subdural abscess: a case report.

机构信息

School of Biomedical Engineering and Imaging Sciences, King's College London, St Thomas' Hospital, London, SE1 7EH, UK.

Department of Neurosurgery, King's College Hospital, Denmark Hill, London, SE5 9RS, UK.

出版信息

J Med Case Rep. 2023 Apr 1;17(1):116. doi: 10.1186/s13256-023-03872-7.

DOI:10.1186/s13256-023-03872-7
PMID:37004082
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10067307/
Abstract

BACKGROUND

Subdural spinous abscess is a rare pathology that carries significant morbidity if not diagnosed and treated early; of the cases reported in the literature, very few are genuinely spontaneous in nature.

CASE PRESENTATION

Here we demonstrate the case of an otherwise entirely fit and well 56-year-old White, British female presenting with low back pain, bilateral sciatica and sensate urinary retention; lumbar subdural spinous abscess was diagnosed on urgent magnetic resonance imaging and the patient was successfully managed with surgical evacuation and prolonged antibiotic therapy. The patient made a full neurological recovery and was followed-up in the outpatient setting 12 weeks following her initial surgery; she was pain free with normal inflammatory markers and a normal neurological examination. There have been no further consultations and a telephone call at 20 weeks confirmed that she remains well.

CONCLUSIONS

This is the second case reported in the literature of a genuinely spontaneous subdural spinous abscess, which was successfully managed with surgical evacuation following prompt diagnosis. This highlights the need to ensure infective pathologies are kept at the back of one's mind even in the most unlikely circumstances, and that excellent outcomes can be achieved with early surgical intervention.

摘要

背景

硬脊膜下棘突脓肿是一种罕见的疾病,如果不能及早诊断和治疗,会带来严重的发病率;在文献中报道的病例中,真正自发的病例非常少。

病例介绍

在这里,我们展示了一位 56 岁的白人、英国女性的病例,她身体状况良好,没有任何其他疾病,仅出现腰痛、双侧坐骨神经痛和感觉性尿潴留;紧急磁共振成像诊断为腰椎硬脊膜下棘突脓肿,患者通过手术清除和长期抗生素治疗成功得到了治疗。患者完全恢复了神经功能,在初次手术后 12 周进行了门诊随访;她无疼痛,炎症标志物正常,神经检查正常。此后再无就诊,20 周的电话随访确认她仍状况良好。

结论

这是文献中报告的第二例真正自发的硬脊膜下棘突脓肿病例,在迅速诊断后通过手术清除成功得到了治疗。这强调了即使在最不可能的情况下,也要始终牢记感染性疾病的可能性,并且早期手术干预可以获得良好的结果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5096/10067307/cb781d30ccce/13256_2023_3872_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5096/10067307/18822b33c3a3/13256_2023_3872_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5096/10067307/cfefb84496f1/13256_2023_3872_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5096/10067307/cb781d30ccce/13256_2023_3872_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5096/10067307/18822b33c3a3/13256_2023_3872_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5096/10067307/cfefb84496f1/13256_2023_3872_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5096/10067307/cb781d30ccce/13256_2023_3872_Fig3_HTML.jpg

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本文引用的文献

1
Spinal infection with intraspinal abscess or empyema and acute myelopathy: comparative analysis of diagnostics, therapy, complications and outcome in primary care.脊柱感染伴椎管内脓肿或积脓和急性脊髓病:基层医疗中的诊断、治疗、并发症和结局的对比分析。
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Surgical Outcome of Spinal Subdural Abscesses: A Report of Four Consecutive Patients and Brief Review of the Literature.脊髓硬膜下脓肿的手术结果:4例连续患者的报告及文献简要回顾
J Neurol Surg A Cent Eur Neurosurg. 2023 Jan;84(1):77-90. doi: 10.1055/s-0041-1739210. Epub 2022 Jan 18.
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Intradural Abscess of the in an Otherwise Healthy Patient.
一名健康患者的硬脊膜内脓肿
Case Rep Surg. 2019 Jan 22;2019:4860420. doi: 10.1155/2019/4860420. eCollection 2019.
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Spinal Intramedullary Abscess Secondary to Dermal Sinus in Children.儿童皮肤窦道继发脊髓髓内脓肿
Eur J Pediatr Surg. 2019 Jun;29(3):229-238. doi: 10.1055/s-0038-1655736. Epub 2018 Jun 1.
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Spinal subdural abscess: a rare complication of decubitus ulcer.脊髓硬膜下脓肿:褥疮溃疡的一种罕见并发症。
Clin Med Res. 2014 Sep;12(1-2):68-72. doi: 10.3121/cmr.2013.1174. Epub 2014 Mar 25.
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Thoracolumbosacral spinal subdural abscess: magnetic resonance imaging appearance and limited surgical management.胸腰骶椎管硬膜下脓肿:磁共振成像表现与有限的手术治疗。
Spine (Phila Pa 1976). 2013 Jun 1;38(13):E844-7. doi: 10.1097/BRS.0b013e31828d5f30.
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Infections of the spinal subdural space in children: a series of 11 contemporary cases and review of all published reports. A multinational collaborative effort.儿童脊髓硬膜下间隙感染:11例当代病例系列及所有已发表报告的综述。一项多国合作研究。
Childs Nerv Syst. 2013 Jan;29(1):105-17. doi: 10.1007/s00381-012-1916-4. Epub 2012 Sep 30.
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Spinal epidural abscess: current diagnosis and management.脊髓硬膜外脓肿:当前的诊断与治疗。
Curr Infect Dis Rep. 2010 Nov;12(6):484-91. doi: 10.1007/s11908-010-0140-1.
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Postoperative central nervous system infection: incidence and associated factors in 2111 neurosurgical procedures.术后中枢神经系统感染:2111例神经外科手术的发生率及相关因素
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