Suppr超能文献

罕见病例报告:半膜肌-内侧副韧带滑囊腱鞘软骨瘤病。

A rare case report of tenosynovial chondromatosis of the semimembranosus-medial collateral ligament bursa.

机构信息

Department of Molecular & Comparative Pathobiology, The Johns Hopkins University School of Medicine, Baltimore, MD, USA.

Department of Comparative Pathobiology, Cummings School of Veterinary Medicine, Tufts University, North Grafton, MA, USA.

出版信息

BMC Musculoskelet Disord. 2023 Apr 1;24(1):251. doi: 10.1186/s12891-023-06337-6.

Abstract

BACKGROUND

Synovial chondromatosis is an uncommon metaplastic process of the synovial lining that results in the formation of cartilaginous nodules within joints or their associated bursae or tendon sheaths. Radiologic evidence of mineralized bodies within these structures is typically pathognomonic for this condition. Extraarticular chondromatosis is rarer than intraarticular chondromatosis, and the knee is affected less frequently than the smaller joints of the hands and feet. To our knowledge, no reports describing this condition in the semimembranosus-medial collateral ligament (SM-MCL) bursa have been published.

CASE PRESENTATION

We describe a case of tenosynovial chondromatosis in a 37-year-old woman. The case was atypical for both the location within the SM-MCL bursa and the paucity of radiodense or hypointense changes to support a clinical suspicion of chondroid metaplasia on radiographs and T2-weighted MRI, respectively. Recreational weightlifting and swimming by the patient were impaired by chronic pain, and restricted range of motion of the ipsilateral knee persisted despite extensive skilled physical therapy and injections of both corticosteroids and platelet-rich plasma. Thirteen months after a diagnostic and therapeutic knee arthroscopy, open surgical excision of the SM-MCL bursal body was performed, and knee pain and range of motion improved by the 6-week postoperative reevaluation. Pathologic evaluation of the excised tissue was consistent with tenosynovial chondromatosis.

CONCLUSIONS

Synovial chondromatosis should be considered in the differential diagnosis for recalcitrant bursitis, even in the absence of classic imaging findings.

摘要

背景

滑膜软骨瘤病是一种少见的滑膜衬里化生过程,导致关节内或其相关滑囊或腱鞘内形成软骨结节。这些结构内有矿化体的放射学证据通常是该疾病的特征性表现。关节外软骨瘤病比关节内软骨瘤病少见,膝关节比手和脚的小关节受影响的频率更低。据我们所知,尚未有文献报道过半膜肌-内侧副韧带(SM-MCL)滑囊内的这种情况。

病例介绍

我们描述了一位 37 岁女性的腱鞘滑膜软骨瘤病病例。该病例在 SM-MCL 滑囊内的位置以及缺乏放射密度或低信号改变均不典型,分别支持放射学和 T2 加权 MRI 上对软骨样化生的临床怀疑。患者因慢性疼痛而无法进行常规举重和游泳,尽管接受了广泛的专业物理治疗和皮质类固醇及富含血小板的血浆注射,但同侧膝关节的活动范围仍受限,疼痛持续存在。在膝关节诊断性和治疗性关节镜检查后 13 个月,进行了 SM-MCL 滑囊体的开放性手术切除,膝关节疼痛和活动范围在 6 周的术后评估时得到改善。切除组织的病理评估与腱鞘滑膜软骨瘤病一致。

结论

即使缺乏典型影像学发现,滑膜软骨瘤病也应纳入难治性滑囊炎的鉴别诊断中。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/64fa/10067226/8ded26e763fb/12891_2023_6337_Fig1_HTML.jpg

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验