Yoshida S, Udou T, Mizuguchi Y, Tanabe T
J Clin Microbiol. 1986 Jan;23(1):192-4. doi: 10.1128/jcm.23.1.192-194.1986.
A strain of Salmonella choleraesuis subsp. choleraesuis serovar paratyphi-A isolated from the blood of a febrile patient grew into filaments on a nutrient agar containing various salts, such as NaCl, KCl, MgCl2, NH4Cl, (NH4)2SO4, or (NH4)2HPO4, at concentrations of 50 to 400 mM. The filamentous cells were nonseptate and multinucleate, and they had colony-forming ability. This mutant strain, however, did not show filamentous growth in liquid media which contained the same salts. On nutrient agar containing 20% sucrose but no salts, some of the cells formed large spheroplasts. Both ampicillin treatment and in vivo environment may in part be responsible for the induction of the mutant strain.
从一名发热患者血液中分离出的猪霍乱沙门氏菌猪霍乱亚种甲型副伤寒血清型菌株,在含有50至400 mM浓度的各种盐(如NaCl、KCl、MgCl2、NH4Cl、(NH4)2SO4或(NH4)2HPO4)的营养琼脂上生长成丝状。丝状细胞无隔膜且多核,具有集落形成能力。然而,该突变菌株在含有相同盐类的液体培养基中未表现出丝状生长。在含有20%蔗糖但无盐的营养琼脂上,一些细胞形成了大的原生质球。氨苄青霉素处理和体内环境可能在一定程度上导致了该突变菌株的诱导。