病例报告：复合套细胞淋巴瘤和经典霍奇金淋巴瘤。
Case report: Composite mantle cell lymphoma and classical Hodgkin lymphoma.
机构信息
Department of Pathology, Qilu Hospital (Qingdao), Cheeloo College of Medicine, Shandong University, Qingdao, China.
Huayin Health Hematopathology Comprehensive Diagnostic Center, Chengdu Huayin Medical Laboratory Center, Chengdu, China.
出版信息
Pathol Oncol Res. 2023 Mar 17;29:1611051. doi: 10.3389/pore.2023.1611051. eCollection 2023.
Composite mantle cell lymphoma and classical Hodgkin lymphoma is very rare and the actual origin of it is still unclear. Here we reported a new case of composite mantle cell lymphoma and classical Hodgkin lymphoma and analyzed its molecular changes. Eight mutations were identified in its Hodgkin component through next-generation sequencing. In addition, we reviewed the published cases of composite mantle cell lymphoma and classical Hodgkin lymphoma and summarized the molecular changes of reported cases as well as the current case to explore the possible pathway of histogenesis.
复合套细胞淋巴瘤和经典霍奇金淋巴瘤非常罕见，其实际起源仍不清楚。在这里，我们报告了一例新的复合套细胞淋巴瘤和经典霍奇金淋巴瘤，并分析了其分子变化。通过下一代测序，在其霍奇金成分中鉴定出 8 个突变。此外，我们复习了已发表的复合套细胞淋巴瘤和经典霍奇金淋巴瘤病例，并总结了报道病例以及本病例的分子变化，以探讨组织发生的可能途径。
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