Olutoye A S, Agboola A D, Bello O O
Department of Obstetrics and Gynecology, University College Hospital, Ibadan, Nigeria.
Dpartment of Obstetrics and Gynecology, College of Medicine, University of Ibadan, Ibadan, Nigeria.
Ann Ib Postgrad Med. 2022 Jun;20(1):32-39.
Puerperal sepsis is one of the leading causes of pregnancy-related maternal morbidity and mortality in developing countries. This study explored the complications, treatment modalities, and management outcomes of puerperal sepsis.
A 10-year retrospective review of women managed for puerperal sepsis at University College Hospital, Ibadan, Nigeria between January 2009 and December 2018. Information on their socio-demographic and obstetrics characteristics, presenting complaints, treatment modalities, complications, and outcomes were obtained from the medical records. Data was analyzed with SPSS version 20. Descriptive statistics was done and results were presented in tables and chart.
The prevalence of puerperal sepsis during the period reviewed was 0.83%. The mean age of the women was 29.0±6.7 years. The primiparous women 53(33.5%) were mostly affected. 25(15.8%) was the most common organism isolated and most sensitive to the third generation of Cephalosporin and Quinolones. Anaemia 90(56.8%) was the most common complication and all the women had intravenous antibiotics while about half (46.5%) of those with abdominopelvic collections were managed surgically via laparotomy. The case fatality rate was 16.5%.
Despite the low prevalence of puerperal sepsis within the period reviewed, a high case fatality was recorded. Cephalosporin and Quinolones should be considered in managing puerperal sepsis in our facility but more importantly prevention of maternal sepsis is essential.
产褥期败血症是发展中国家与妊娠相关的孕产妇发病和死亡的主要原因之一。本研究探讨了产褥期败血症的并发症、治疗方式及管理结果。
对2009年1月至2018年12月期间在尼日利亚伊巴丹大学学院医院接受产褥期败血症治疗的女性进行了为期10年的回顾性研究。从病历中获取了她们的社会人口统计学和产科特征、主诉、治疗方式、并发症及结果等信息。使用SPSS 20版软件进行数据分析。进行描述性统计，并以表格和图表形式呈现结果。
在所审查期间，产褥期败血症的患病率为0.83%。这些女性的平均年龄为29.0±6.7岁。初产妇53例（33.5%）受影响最为严重。分离出的最常见病原体为25株（15.8%），对第三代头孢菌素和喹诺酮类药物最为敏感。贫血90例（56.8%）是最常见的并发症，所有女性均接受了静脉抗生素治疗，而约一半（46.5%）有腹腔盆腔积液的女性通过剖腹手术进行了外科治疗。病死率为16.5%。
尽管在所审查期间产褥期败血症的患病率较低，但病死率较高。在我们的医疗机构中，治疗产褥期败血症时应考虑使用头孢菌素和喹诺酮类药物，但更重要的是预防孕产妇败血症至关重要。
