Kumar Aalok, Srivastav Tanmay
Department of Ophthalmology, Regional Institute of Ophthalmology, Banaras Hindu University, Varanasi, Uttar Pradesh, India.
Oman J Ophthalmol. 2023 Feb 21;16(1):35-38. doi: 10.4103/ojo.ojo_147_22. eCollection 2023 Jan-Apr.
The study analyzed the association of head posture on intraocular pressure (IOP). The study aimed to evaluate and measure the changes in IOP and heart rate (HR) of human beings on head-down posture. The study included 105 patients at the department of ophthalmology of a tertiary care center in India.
Patients underwent applanation tonometry and HR variability (HRV) analysis before and after 20 min of head-down posture (approximately 20°). The IOP and HRV were measured.
The statistical methods of Paired -test and linear regression analysis were applied. < 0.05 was defined as statistically significant.
After 20 min of the 20° head-down position, an increase in IOP was significant from 15.0 ± 2.0 mmHg to 18.0 ± 2.3 mmHg ( < 0.001). A decrease in HR was also significant from 78 ± 10.48 bpm to 72 ± 10.52 bpm after the head-down position for 20 min ( < 0.05).
These outcomes presented the first evidence of the activation of the parasympathetic nervous system in the head-down position which might cause decreased HR and the collapse of Schlemm's canal lumen, which in turn leads to the increased IOP.
本研究分析了头部姿势与眼压（IOP）之间的关联。该研究旨在评估和测量人体在头低位姿势下眼压和心率（HR）的变化。该研究纳入了印度一家三级医疗中心眼科的105名患者。
患者在头低位姿势（约20°）20分钟前后接受压平眼压测量和心率变异性（HRV）分析。测量眼压和HRV。
应用配对检验和线性回归分析的统计方法。P<0.05被定义为具有统计学意义。
在20°头低位姿势20分钟后，眼压从15.0±2.0mmHg显著升高至18.0±2.3mmHg（P<0.001）。头低位姿势20分钟后，心率也从78±10.48次/分钟显著降低至72±10.52次/分钟（P<0.05）。
这些结果首次证明了头低位姿势下副交感神经系统的激活，这可能导致心率降低和施莱姆管腔塌陷，进而导致眼压升高。
