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持续性、瘙痒性、红棕色丘疹和斑块:成人斯蒂尔病的非典型表现。

Persistent, Pruritic, Reddish-Brown Papules and Plaques: An Atypical Presentation of Adult-Onset Still's Disease.

作者信息

Whittington Carli, Lapides Rebecca, Morley Keith, Greene Laura

机构信息

Department of Medicine, Division of Dermatology, University of Vermont Medical Center, Burlington, USA.

Pathology and Laboratory Medicine/Dermatopathology, University of Vermont Medical Center, Burlington, USA.

出版信息

Cureus. 2023 Feb 28;15(2):e35587. doi: 10.7759/cureus.35587. eCollection 2023 Feb.

Abstract

Adult-onset Still's disease (AOSD) is a systemic inflammatory condition characterized by recurrent fevers and a dermatologic eruption. The eruption is classically described as migratory and evanescent, composed of salmon-pink to erythematous macules, patches, and papules. However, a much rarer skin rash can also be seen in the setting of AOSD. This eruption has a different morphology, appearing as fixed, extremely pruritic papules and plaques. The histology of this atypical form of AOSD is distinct from that of the more common evanescent eruption. Management of AOSD is multi-faceted, aimed at controlling both the acute and chronic phases. Increased awareness of this more uncommon cutaneous presentation of AOSD is vital so that the appropriate diagnosis can be rendered. Herein, the authors describe an atypical presentation of AOSD in a 44-year-old male patient who presented with persistent, pruritic, brownish papules and plaques on the trunk and extremities.

摘要

成人斯蒂尔病(AOSD)是一种以反复发热和皮疹为特征的全身性炎症性疾病。皮疹通常被描述为游走性和一过性的,由鲑鱼粉红色至红斑性斑疹、斑片和丘疹组成。然而,在AOSD患者中也可见到一种罕见得多的皮疹。这种皮疹具有不同的形态,表现为固定的、极度瘙痒的丘疹和斑块。这种非典型形式的AOSD的组织学与更常见的一过性皮疹不同。AOSD的治疗是多方面的,旨在控制急性期和慢性期。提高对AOSD这种较不常见皮肤表现的认识至关重要,以便能够做出正确的诊断。在此,作者描述了一名44岁男性患者的AOSD非典型表现,该患者躯干和四肢出现持续的、瘙痒的、褐色丘疹和斑块。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/637f/10062437/d8a13f44f327/cureus-0015-00000035587-i01.jpg

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