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伯基特淋巴瘤的非典型表现:孤立性腹膜受累,并与因瓦伯格效应继发的难治性B型乳酸酸中毒和低血糖相关。

Atypical Presentation of Burkitt Lymphoma With Isolated Peritoneal Involvement and Association With Refractory Type B Lactic Acidosis and Hypoglycemia Secondary to the Warburg Effect.

作者信息

Abbas Aymen K, Osman Ahmed Y

机构信息

Internal Medicine, Sheikh Khalifa Medical City, Abu Dhabi, ARE.

出版信息

Cureus. 2023 Feb 27;15(2):e35521. doi: 10.7759/cureus.35521. eCollection 2023 Feb.

Abstract

Lactic acidosis is considered to be one of the most common causes of high anion gap metabolic acidosis in hospitalized patients. Warburg effect can present with type B lactic acidosis and is considered to be a rare but well-known complication of hematological malignancies. Here, we present the case of a 39-year-old male who had type B lactic acidosis and recurrent hypoglycemia secondary to newly diagnosed Burkitt lymphoma. This case highlights the importance of considering malignancy workup in any case of unexplained type B lactic acidosis with vague clinical presentation, which can aid in early diagnosis and management.

摘要

乳酸性酸中毒被认为是住院患者高阴离子间隙代谢性酸中毒最常见的原因之一。瓦伯格效应可表现为B型乳酸性酸中毒,被认为是血液系统恶性肿瘤一种罕见但广为人知的并发症。在此,我们报告一例39岁男性患者,其因新诊断的伯基特淋巴瘤继发B型乳酸性酸中毒和反复低血糖。该病例强调了在任何临床表现模糊的不明原因B型乳酸性酸中毒病例中考虑进行恶性肿瘤检查的重要性,这有助于早期诊断和治疗。

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