玻璃体腔内注入空气的气动玻璃体溶解术治疗局限性玻璃体黄斑牵引。
Pneumatic Vitreolysis With Intravitreal Air for Focal Vitreomacular Traction.
作者信息
Seamone Mark E, Rubin Uriel, Grewal Parampal S, Greve Mark
机构信息
Department of Ophthalmology & Visual Sciences, University of Alberta, Edmonton, Alberta, Canada.
出版信息
J Vitreoretin Dis. 2020 Nov 6;5(4):348-353. doi: 10.1177/2474126420962649. eCollection 2021 Jul-Aug.
PURPOSE
To determine whether pneumatic vitreolysis with intravitreal air is effective for focal vitreomacular traction (VMT).
METHODS
We conducted a retrospective consecutive case series of 20 eyes from 19 individuals with focal VMT who underwent pneumatic vitreolysis with intravitreal air (January 2017 to November 2018). We analyzed patients via spectral-domain optical coherence tomography before intravitreal air injection and at 1 month. The primary outcome measure was release of VMT.
RESULTS
We observed release of VMT in 55% of individuals. An analysis limited to phakic eyes demonstrated release of VMT in 69%, and 65% developed improved best-corrected visual acuity. Individuals with persistent VMT and visual improvement had a significant reduction in angle of vitreoretinal insertion ( < .01), area under VMT ( < .05), and subfoveal cyst area ( < .05).
CONCLUSIONS
Intravitreal air is an effective treatment for focal VMT. In individuals with persistent VMT, visual-acuity improvement was associated with a reduction in overall VMT.
目的
确定玻璃体腔内注入空气进行气体性玻璃体松解术治疗局限性玻璃体黄斑牵引（VMT）是否有效。
方法
我们对19例局限性VMT患者的20只眼进行了回顾性连续病例系列研究，这些患者于2017年1月至2018年11月接受了玻璃体腔内注入空气的气体性玻璃体松解术。我们在玻璃体腔内注入空气前及术后1个月通过光谱域光学相干断层扫描对患者进行分析。主要观察指标为VMT的解除。
结果
我们观察到55%的患者VMT得到解除。仅对有晶状体眼的分析显示，69%的患者VMT得到解除，65%的患者最佳矫正视力得到改善。VMT持续存在但视力改善的患者，玻璃体视网膜插入角显著减小（P<0.01），VMT下面积显著减小（P<0.05），黄斑中心凹下囊肿面积显著减小（P<0.05）。
结论
玻璃体腔内注入空气是治疗局限性VMT的有效方法。在VMT持续存在的患者中，视力改善与总体VMT的减少有关。
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