伴有感染和溃疡性结肠炎的匐行性脉络膜炎
Serpiginous Choroiditis Presenting in Association With Infection and Ulcerative Colitis.
作者信息
Pollmann André S, Mishra Amit V, Betsch Devin M, Francisconi Carolina L M
机构信息
Department of Ophthalmology and Visual Sciences, Dalhousie University, Halifax, Nova Scotia, Canada.
出版信息
J Vitreoretin Dis. 2020 Sep 2;5(2):177-181. doi: 10.1177/2474126420946922. eCollection 2021 Mar-Apr.
PURPOSE
This work reports a case of serpiginous choroiditis (SC) in association with ulcerative colitis and infection.
METHODS
A case report is discussed.
RESULTS
A 35-year-old man with a history of ulcerative colitis and recently treated infection presented with a rapid decline in central visual acuity in both eyes. Examination findings included geographic creamy-white lesions extending from the peripapillary region in both eyes. Multimodal imaging and negative infectious workup results supported the diagnosis of SC. Visual acuity and examination findings improved after initiation of systemic prednisone therapy. Adalimumab was initiated as a steroid-sparing treatment. At the last follow-up, 5 months after the initial presentation, SC and ulcerative colitis both remain in remission.
CONCLUSIONS
SC has been previously described in patients with systemic disorders, including autoimmune conditions. This patient developed SC following infection and in the context of active ulcerative colitis. To our knowledge, this is the first report of SC in association with these entities.
目的
本研究报告一例匐行性脉络膜炎（SC）合并溃疡性结肠炎及感染的病例。
方法
讨论一例病例报告。
结果
一名35岁男性，有溃疡性结肠炎病史且近期有感染治疗史，双眼中心视力迅速下降。检查发现包括双眼从视乳头周围区域延伸的地图状乳脂样病变。多模态成像及感染相关检查结果阴性支持匐行性脉络膜炎的诊断。开始全身使用泼尼松治疗后，视力及检查结果有所改善。开始使用阿达木单抗作为激素替代治疗。在初次就诊5个月后的最后一次随访中，匐行性脉络膜炎和溃疡性结肠炎均处于缓解期。
结论
此前已在包括自身免疫性疾病在内的全身性疾病患者中描述过匐行性脉络膜炎。该患者在感染后及活动性溃疡性结肠炎背景下发生了匐行性脉络膜炎。据我们所知，这是首例匐行性脉络膜炎合并这些疾病实体的报告。
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