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模仿匐行性脉络膜病变的抗磷脂抗体综合征

Antiphospholipid antibody syndrome mimicking serpiginous choroidopathy.

作者信息

Tang Johnny, Fillmore Gary, Nussenblatt Robert B

机构信息

Research Service, Louis Stokes Cleveland DVA Medical Center, Cleveland, Ohio, USA.

出版信息

Ocul Immunol Inflamm. 2009 Jul-Aug;17(4):278-81. doi: 10.1080/09273940902989340.

Abstract

PURPOSE

To report a patient with antiphospholipid antibody syndrome (APS) presenting with ocular findings similar to serpiginous choroidopathy.

METHODS

Case report.

RESULTS

A man complained of blurred vision. Examination revealed vitritis, vasculitis, retinal ischemia, and neovascularization. Clinical and angiographic features consistent with serpiginous choroidopathy were found. An evaluation for uveitis and retinal vasculitis was remarkable for APS.

CONCLUSION

This case expands on previously reported ocular findings associated with APS. Although the role of antiphospholipid antibodies in the pathogenesis remains undefined, the findings, including the serpiginous-like choroidopathy, can be reasonably explained by vaso-occlusion in both the retinal and choroidal vasculature.

摘要

目的

报告一例抗磷脂抗体综合征(APS)患者,其眼部表现类似于匐行性脉络膜病变。

方法

病例报告。

结果

一名男性主诉视力模糊。检查发现玻璃体炎、血管炎、视网膜缺血和新生血管形成。发现了与匐行性脉络膜病变一致的临床和血管造影特征。对葡萄膜炎和视网膜血管炎的评估显示该患者患有APS。

结论

本病例扩展了先前报道的与APS相关的眼部表现。尽管抗磷脂抗体在发病机制中的作用尚不清楚,但包括匐行性脉络膜病变样表现在内的这些发现,可以通过视网膜和脉络膜血管系统的血管阻塞得到合理的解释。

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