Tokumitsu Keita, Yasui-Furukori Norio, Adachi Naoto, Kubota Yukihisa, Watanabe Yoichiro, Miki Kazuhira, Azekawa Takaharu, Edagawa Koji, Katsumoto Eiichi, Hongo Seiji, Goto Eiichiro, Ueda Hitoshi, Kato Masaki, Nakagawa Atsuo, Kikuchi Toshiaki, Tsuboi Takashi, Watanabe Koichiro, Shimoda Kazutaka, Yoshimura Reiji
Department of Psychiatry, Dokkyo Medical University School of Medicine, Tochigi, Japan.
The Japanese Society of Clinical Neuropsychopharmacology, Tokyo, Japan.
Front Psychiatry. 2023 Mar 16;14:1078045. doi: 10.3389/fpsyt.2023.1078045. eCollection 2023.
Bipolar disorder is a psychiatric disorder that causes recurrent manic and depressive episodes, leading to decreased levels of social functioning and suicide. Patients who require hospitalization due to exacerbation of bipolar disorder have been reported to subsequently have poor psychosocial functioning, and so there is a need to prevent hospitalization. On the other hand, there is a lack of evidence regarding predictors of hospitalization in real-world clinical practice.
The multicenter treatment survey on bipolar disorder (MUSUBI) in Japanese psychiatric clinics was an observational study conducted to provide evidence regarding bipolar disorder in real-world clinical practice. Psychiatrists were asked, as part of a retrospective medical record survey, to fill out a questionnaire about patients with bipolar disorder who visited 176 member clinics of the Japanese Association of Neuro-Psychiatric Clinics. Our study extracted baseline patient characteristics from records dated between September and October 2016, including comorbidities, mental status, duration of treatment, Global Assessment of Functioning (GAF) score, and pharmacological treatment details. The incidence and predictors of hospitalization among patients with bipolar disorder over a 1-year period extending from that baseline to September-October 2017 were examined.
In total, 2,389 participants were included in our study, 3.06% of whom experienced psychiatric hospitalization over the course of 1 year from baseline. Binomial logistic regression analysis revealed that the presence of psychiatric hospitalization was correlated with bipolar I disorder, lower baseline GAF scores, unemployment, substance abuse and manic state.
Our study revealed that 3.06% of outpatients with bipolar disorder were subjected to psychiatric hospitalization during a 1-year period that extended to September-October 2017. Our study suggested that bipolar I disorder, lower baseline GAF scores, unemployment, substance abuse and baseline mood state could be predictors of psychiatric hospitalization. These results may be useful for clinicians seeking to prevent psychiatric hospitalization for bipolar disorder.
双相情感障碍是一种精神疾病，会导致反复出现躁狂和抑郁发作，从而导致社会功能水平下降和自杀。据报道，因双相情感障碍病情加重而需要住院治疗的患者，其随后的心理社会功能较差，因此有必要预防住院治疗。另一方面，在现实世界的临床实践中，关于住院治疗预测因素的证据不足。
日本精神科诊所的双相情感障碍多中心治疗调查（MUSUBI）是一项观察性研究，旨在为现实世界临床实践中的双相情感障碍患者提供证据。作为回顾性病历调查的一部分，精神科医生被要求填写一份关于就诊于日本神经精神科诊所协会176家成员诊所的双相情感障碍患者的问卷。我们研究提取了2,
我们的研究共纳入2,
结论 :本研究显示，在截至2017年9月至10月的1年时间里，3, 这些结果可能对寻求预防双相情感障碍患者精神科住院治疗的临床医生有用。
