视网膜劈裂症和视网膜脱离的广角眼底自发荧光模式的比较评估
Comparative Assessment of Widefield Fundus Autofluorescence Patterns in Retinoschisis and Retinal Detachment.
作者信息
Cao Jessica L, Conti Thais F, Hom Grant L, Babiuch Amy S, Greenlee Tyler, Ehlers Justis P, Rachitskaya Aleksandra, Sharma Sumit, Yuan Alex, Kaiser Peter K, Singh Rishi P
机构信息
Cole Eye Institute, Cleveland Clinic Foundation, Cleveland, OH, USA.
Center for Ophthalmic Bioinformatics, Cole Eye Institute, Cleveland Clinic Foundation, Cleveland, OH, USA.
出版信息
J Vitreoretin Dis. 2020 Mar 3;4(4):286-292. doi: 10.1177/2474126420907020. eCollection 2020 Jul-Aug.
PURPOSE
This article characterizes widefield fundus autofluorescence (WF-FAF) patterns in retinoschisis (RS), retinal detachment (RD), and combined retinoschisis-detachment (RS/RD), and to correlate them with spectral-domain optical coherence tomography (SD-OCT) findings.
METHODS
A retrospective case series of 13 eyes with senile RS, RD, or RS/RD is presented. One eye underwent imaging of 2 areas within the retina, resulting in 14 data points. Independent, masked graders classified pathology on SD-OCT as RS, RD, or RS/RD and graded WF-FAF images for either hypoautofluorescent areas or mixed autofluorescence (AF) (hyper-AF, iso-AF, hyper-AF with hypo-AF, hyper-AF with iso-AF, or hypo-AF with iso-AF).
RESULTS
There was no statistically significant correlation between the autofluorescence pattern and the type of retinal abnormality ( = .74).
CONCLUSIONS
High variability was found in the characterization of WF-FAF in patients with RS and RD. SD-OCT remains the criterion-standard imaging modality in distinguishing RS from RD in clinically ambiguous cases.
目的
本文描述视网膜劈裂（RS）、视网膜脱离（RD）及合并视网膜劈裂-脱离（RS/RD）的广角眼底自发荧光（WF-FAF）模式，并将其与频域光学相干断层扫描（SD-OCT）结果相关联。
方法
呈现13例患有老年性RS、RD或RS/RD的病例系列回顾性研究。一只眼睛对视网膜内的2个区域进行成像，产生14个数据点。独立的、不知情的分级人员将SD-OCT上的病变分类为RS、RD或RS/RD，并对WF-FAF图像上的低自发荧光区域或混合自发荧光（AF）（高AF、等AF、高AF伴低AF、高AF伴等AF或低AF伴等AF）进行分级。
结果
自发荧光模式与视网膜异常类型之间无统计学显著相关性（ = 0.74）。
结论
在RS和RD患者的WF-FAF特征中发现高度变异性。在临床诊断不明确的病例中，SD-OCT仍然是区分RS与RD的标准成像方式。
Zotero 插件