• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

精氨酰转移酶:个人见解与历史视角

Arginyltransferase: A Personal and Historical Perspective.

作者信息

Soffer Richard L

机构信息

Weill Medical College, Cornell University, New York, NY, USA.

出版信息

Methods Mol Biol. 2023;2620:21-25. doi: 10.1007/978-1-0716-2942-0_3.

DOI:10.1007/978-1-0716-2942-0_3
PMID:37010744
Abstract

In the late 1960s and early 1970s, characterization of arginylation has been spearheaded via biochemical studies that enabled the first characterization of ATE1 and its substrate specificity. This chapter summarized the recollections and insights from the era of research that followed from the original discovery of arginylation and led up to the identification of the arginylation enzyme.

摘要

在20世纪60年代末和70年代初,精氨酸化的表征工作是通过生化研究率先开展的,这些研究实现了对ATE1及其底物特异性的首次表征。本章总结了从精氨酸化的最初发现到精氨酸化酶鉴定这一研究时代的回忆与见解。

相似文献

1
Arginyltransferase: A Personal and Historical Perspective.精氨酰转移酶:个人见解与历史视角
Methods Mol Biol. 2023;2620:21-25. doi: 10.1007/978-1-0716-2942-0_3.
2
Arginyltransferase: A Personal and Historical Perspective.精氨酰转移酶:个人视角与历史回顾
Methods Mol Biol. 2015;1337:19-23. doi: 10.1007/978-1-4939-2935-1_3.
3
Assaying for Arginyltransferase Activity and Specificity by Peptide Arrays.通过肽阵列分析精氨酰转移酶活性和特异性
Methods Mol Biol. 2023;2620:123-127. doi: 10.1007/978-1-0716-2942-0_17.
4
Post-translational protein arginylation in the normal nervous system and in neurodegeneration.正常神经系统和神经退行性变中的蛋白质翻译后精氨酰化
J Neurochem. 2016 Aug;138(4):506-17. doi: 10.1111/jnc.13708. Epub 2016 Jul 5.
5
Global Analysis of Post-Translational Side-Chain Arginylation Using Pan-Arginylation Antibodies.泛精氨酸化抗体对翻译后侧链精氨酸化的全局分析。
Mol Cell Proteomics. 2023 Nov;22(11):100664. doi: 10.1016/j.mcpro.2023.100664. Epub 2023 Oct 12.
6
tRNA-Derived Fragments Can Serve as Arginine Donors for Protein Arginylation.转运RNA衍生片段可作为蛋白质精氨酰化的精氨酸供体。
Cell Chem Biol. 2020 Jul 16;27(7):839-849.e4. doi: 10.1016/j.chembiol.2020.05.013. Epub 2020 Jun 16.
7
Assaying ATE1 Activity In Vitro.体外测定ATE1活性。
Methods Mol Biol. 2023;2620:113-117. doi: 10.1007/978-1-0716-2942-0_15.
8
The preparation of recombinant arginyltransferase 1 (ATE1) for biophysical characterization.重组精氨酰-tRNA 合成酶 1(ATE1)的制备用于生物物理特性分析。
Methods Enzymol. 2023;679:235-254. doi: 10.1016/bs.mie.2022.07.036. Epub 2022 Aug 31.
9
Posttranslational arginylation enzyme Ate1 affects DNA mutagenesis by regulating stress response.翻译后修饰精氨酰化酶Ate1通过调节应激反应影响DNA诱变。
Cell Death Dis. 2016 Sep 29;7(9):e2378. doi: 10.1038/cddis.2016.284.
10
Analyzing N-terminal Arginylation through the Use of Peptide Arrays and Degradation Assays.通过使用肽阵列和降解试验分析N端精氨酰化
J Biol Chem. 2016 Sep 30;291(40):20976-20992. doi: 10.1074/jbc.M116.747956. Epub 2016 Aug 10.

本文引用的文献

1
A mutant of Saccharomyces cerevisiae defective in arginyl-tRNA-protein transferase.精氨酸-tRNA 蛋白转移酶缺陷的酿酒酵母突变体。
Curr Genet. 1983 Jul;7(4):285-8. doi: 10.1007/BF00376073.
2
AMINO ACID INCORPORATION INTO PROTEIN BY A CELL FREE SYSTEM FROM PLASMA CELL TUMORS.
Acta Unio Int Contra Cancrum. 1964;20:932-6.
3
A SOLUBLE AMINO ACID-INCORPORATING SYSTEM FROM RAT LIVER.大鼠肝脏中的一种可溶性氨基酸掺入系统。
Biochim Biophys Acta. 1963 Nov 22;76:474-7.
4
Incorporation of arginine by a soluble system from sheep thyroid.
Biochem Biophys Res Commun. 1966 May 3;23(3):252-8. doi: 10.1016/0006-291x(66)90537-7.
5
Enzymic modification of proteins. I. General characteristics of the arginine-transfer reaction in rabbit liver cytoplasm.
J Mol Biol. 1969 Jul 14;43(1):163-75. doi: 10.1016/0022-2836(69)90086-2.
6
The arginine transfer reaction.
Biochim Biophys Acta. 1968 Jan 29;155(1):228-40. doi: 10.1016/0005-2787(68)90352-3.
7
Enzymatic modification of proteins. II. Purification and properties of the arginyl transfer ribonucleic acid-protein transferase from rabbit liver cytoplasm.蛋白质的酶促修饰。II. 兔肝细胞质中精氨酰转移核糖核酸-蛋白质转移酶的纯化及性质
J Biol Chem. 1970 Feb 25;245(4):731-7.
8
Enzymatic probe for accessibility of NH 2 -terminal residues in immunoglobulins.用于检测免疫球蛋白中氨基末端残基可及性的酶促探针。
Nat New Biol. 1971 Sep 8;233(36):44-5. doi: 10.1038/newbio233044a0.
9
Enzymatic modification of proteins. 4. Arginylation of bovine thyroglobulin.
J Biol Chem. 1971 Mar 10;246(5):1481-4.
10
Enzymatic modification of proteins. VI. Site of acylation of bovine serum albumin in the leucine, phenylalanine-transfer reaction.
J Biol Chem. 1971 Jul 25;246(14):4431-8.