Department of Gastroenterology Vall d'Hebron Hospital Universitari, Vall d'Hebron Barcelona Hospital Campus, Barcelona, Spain.
Department of Gastroenterology, Lozano Blesa University Clinical Hospital, Zaragoza, Spain.
Neurogastroenterol Motil. 2023 Jun;35(6):e14582. doi: 10.1111/nmo.14582. Epub 2023 Apr 3.
Data for Spain from the Rome Foundation Global Epidemiology Study on the disorders of gut-brain interaction (DGBI) were used to assess the national and regional prevalence of all 22 DGBI, the percentage of respondents meeting diagnostic criteria for at least one DGBI, and the impact on burden of disease in our country.
Data were collected through an anonymous, nationwide, and secure Internet survey with multiple built-in quality-assurance techniques that included the Rome IV diagnostic questionnaire and an in-depth supplemental questionnaire.
The survey was completed by 2072 adult Spanish participants (50.2% female) with a mean age of 45.67 ± 15.44 years with a good representative national distribution. 43.6% (41.5%-45.8%) met diagnostic criteria for at least one DGBI, with 8.2% for any esophageal disorder, 12.1% for any gastroduodenal disorder, 30.1% for any bowel disorder, and 11.5% for any anorectal disorder. Functional constipation was the most prevalent DGBI in Spain (12.8%). We found that proctalgia fugax (9.3%), unspecified bowel disorders (10.8%), and functional dysphagia (5.6%) showed unexplained high rates in our country. DGBI rates were higher for women. Having any DGBI was negatively associated with psychosocial variables (including quality of life, somatization, and concern about digestive problems), and associated with increased healthcare utilization.
CONCLUSIONS & INFERENCES: We provide the first comprehensive data on the prevalence and burden of all DGBI in Spain using the Rome IV criteria. The enormous burden of DGBI in Spain highlights the need for specialized training and future research.
使用来自罗马基金会全球肠脑相互作用障碍（DGBI）流行病学研究的西班牙数据，评估了所有 22 种 DGBI 的国家和地区患病率、符合至少一种 DGBI 诊断标准的受访者比例，以及对我国疾病负担的影响。
通过匿名、全国性和安全的互联网调查收集数据，该调查采用了多种内置质量保证技术，包括罗马 IV 诊断问卷和深入的补充问卷。
该调查由 2072 名成年西班牙参与者（50.2%为女性）完成，平均年龄为 45.67±15.44 岁，具有良好的全国代表性分布。43.6%（41.5%-45.8%）符合至少一种 DGBI 的诊断标准，其中 8.2%为任何食管疾病，12.1%为任何胃十二指肠疾病，30.1%为任何肠疾病，11.5%为任何肛肠疾病。功能性便秘是西班牙最常见的 DGBI（12.8%）。我们发现，短暂性肛门直肠痛（9.3%）、未特指的肠疾病（10.8%）和功能性吞咽困难（5.6%）在我国的发病率较高。DGBI 发病率女性较高。患有任何 DGBI 与心理健康变量（包括生活质量、躯体化和对消化问题的关注）呈负相关，与增加医疗保健利用率相关。
我们使用罗马 IV 标准首次提供了西班牙所有 DGBI 的患病率和疾病负担的综合数据。DGBI 在西班牙的巨大负担突显了对专门培训和未来研究的需求。
