Takai H
Nihon Seikeigeka Gakkai Zasshi. 1986 Jan;60(1):1-10.
In spite of all the successful advances in microvascular surgery, the use of arterial graft is still a subject of controversy. To elucidate the advantages and indications of arterial grafts in microsurgery, venous and arterial grafts were transplanted to the femoral artery of the rat, and the former was investigated histopathologically one, two, three, four, six and eight weeks, and the latter one, two, three and four weeks after transplantation. As the results, intimal thickening was noted in neither of the two grafts. In the venous grafts, endotherial cells were almost separated two weeks after transplantation, and the media showed fibrous replacement. In contrast, the intima remained unchanged and the media maintained its layers of smooth muscle cells in the arterial grafts. The arterial grafts showed little post-transplantation change and maintained their pre-transplantation structure, retaining contracting and dilating function. Based on these results, arterial grafts might be applied clinically in microsurgery.
尽管微血管手术取得了诸多成功进展，但动脉移植物的使用仍是一个存在争议的话题。为阐明动脉移植物在显微外科中的优势和适应证，将静脉和动脉移植物移植到大鼠股动脉，对前者在移植后1周、2周、3周、4周、6周和8周进行组织病理学研究，对后者在移植后1周、2周、3周和4周进行研究。结果显示，两种移植物均未出现内膜增厚。在静脉移植物中，移植后2周内皮细胞几乎分离，中膜出现纤维性替代。相比之下，动脉移植物的内膜保持不变，中膜维持平滑肌细胞层。动脉移植物移植后变化很小，保持了移植前的结构，保留了收缩和舒张功能。基于这些结果，动脉移植物可能在显微外科临床应用。
