Department of Pediatrics, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA.
Semin Perinatol. 2023 Jun;47(4):151748. doi: 10.1016/j.semperi.2023.151748. Epub 2023 Mar 17.
Delayed umbilical cord clamping, DCC, a practice in which the umbilical cord is not clamped immediately after birth, promotes placental transfusion to preterm and term neonates. DCC may improve outcomes in preterm neonates by reducing mortality and blood transfusion requirements and increasing iron stores. Despite the recommendations from multiple governing bodies, including the World Health Organization, research on DCC in LMICs remains limited. Given that iron deficiency is prevalent, and most neonatal deaths occur in LMICs, DCC has the potential to improve outcomes in these settings. This article aims to provide a global perspective on DCC in LMICs and to identify knowledge gaps that offer future research opportunities.
延迟脐带夹闭(DCC)是一种在新生儿出生后不立即夹闭脐带的做法,可促进早产儿和足月儿的胎盘输血。DCC 可能通过降低早产儿的死亡率和输血需求以及增加铁储存来改善结局。尽管包括世界卫生组织在内的多个管理机构都提出了建议,但在中低收入国家(LMICs),关于 DCC 的研究仍然有限。鉴于缺铁症普遍存在,而且大多数新生儿死亡发生在 LMICs,因此 DCC 有可能改善这些地区的结局。本文旨在提供一个全球视角来看待中低收入国家的 DCC,并确定知识空白,为未来的研究提供机会。