Academic Urology Unit, University of Aberdeen, Aberdeen, UK.
Guidelines Office, European Association of Urology, Arnhem, Netherlands.
Nat Rev Urol. 2023 Aug;20(8):494-501. doi: 10.1038/s41585-023-00748-9. Epub 2023 Apr 3.
PIONEER is a European network of excellence for big data in prostate cancer consisting of 37 private and public stakeholders from 9 countries across Europe. Many progresses have been done in prostate cancer management, but unanswered questions in the field still exist, and big data could help to answer these questions. The PIONEER consortium conducted a two-round modified Delphi survey aiming at building consensus between two stakeholder groups - health-care professionals and patients with prostate cancer - about the most important questions in the field of prostate cancer to be answered using big data. Respondents were asked to consider what would be the effect of answering the proposed questions on improving diagnosis and treatment outcomes for patients with prostate cancer and to score these questions on a scale of 1 (not important) to 9 (critically important). The mean percentage of participants who scored each of the proposed questions as critically important was calculated across the two stakeholder groups and used to rank the questions and identify the highest scoring questions in the critically important category. The identification of questions in prostate cancer that are important to various stakeholders will help the PIONEER consortium to provide answers to these questions to improve the clinical care of patients with prostate cancer.
PIONEER 是一个专注于前列腺癌大数据的欧洲卓越网络，由来自欧洲 9 个国家的 37 个私营和公共利益相关者组成。在前列腺癌管理方面已经取得了许多进展，但该领域仍存在一些未解决的问题，而大数据可以帮助回答这些问题。PIONEER 联盟进行了两轮改良 Delphi 调查，旨在就使用大数据回答前列腺癌领域最重要问题达成两组利益相关者（医疗保健专业人员和前列腺癌患者）之间的共识。受访者被要求考虑回答拟议问题对改善前列腺癌患者的诊断和治疗结果的影响，并在 1（不重要）到 9（至关重要）的量表上对这些问题进行评分。在两个利益相关者群体中计算了每个拟议问题被评为至关重要的参与者的平均百分比，并用于对问题进行排名，并确定至关重要类别中的得分最高的问题。确定对不同利益相关者重要的前列腺癌问题将有助于 PIONEER 联盟为这些问题提供答案，以改善前列腺癌患者的临床护理。
