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使用柠檬酸酸化透析液进行高容量血液滤过治疗的患者成功妊娠

Success of Pregnancy in a Patient on High-Volume Hemodiafiltration with Citrate-Acidified Dialysate.

作者信息

Pellé Gaëlle, Jalal Eddine Arwa, Rieu Philippe, Attias Julie, Fay Stephanie, Hertig Alexandre

机构信息

Department of Nephrology, Foch Hospital, Suresnes, France.

Hemodialysis Center SIRTA, Argenteuil, France.

出版信息

Case Rep Nephrol Dial. 2023 Mar 31;13(1):15-19. doi: 10.1159/000528725. eCollection 2023 Jan-Dec.

Abstract

Although pregnancy in dialysis patients is rare, recent reports in the literature have shown improvement in pregnancy outcome in this population. Increasing doses of dialysis have led to improvement in fetal prognosis, but recommendations are still lacking, and there are few documented reports of pregnant woman on high-volume online hemodiafiltration. Here, we report the first successful pregnancy in a 28-year-old patient on daily high-volume online post-dilution hemodiafiltration with a citrate dialysate. At 37 weeks and 1 day, she delivered a healthy 2.3 kg baby that did not require neonatal intensive care. This case report suggests that hemodiafiltration with a dialysate acidified with citrate is safe in pregnancy. Further reports and a registry are necessary to confirm that high-volume online hemodiafiltration with a citrate dialysate should be the preferred dialysis modality in pregnant women.

摘要

尽管透析患者怀孕的情况很少见,但近期文献报道显示该人群的妊娠结局有所改善。增加透析剂量已使胎儿预后得到改善,但仍缺乏相关建议,且关于接受高容量在线血液透析滤过的孕妇的文献报道很少。在此,我们报告首例成功妊娠病例,患者为一名28岁女性,每日接受高容量在线后稀释血液透析滤过并使用柠檬酸盐透析液。孕37周零1天时,她产下一名健康的2.3千克婴儿,该婴儿无需新生儿重症监护。本病例报告表明,使用柠檬酸盐酸化的透析液进行血液透析滤过在孕期是安全的。需要更多报告和登记资料来证实,使用柠檬酸盐透析液的高容量在线血液透析滤过应成为孕妇首选的透析方式。

相似文献

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Why choose high volume online post-dilution hemodiafiltration?为什么选择高通量在线后稀释血液透析滤过?
J Nephrol. 2017 Apr;30(2):181-186. doi: 10.1007/s40620-016-0343-0. Epub 2016 Sep 1.

本文引用的文献

4
Pregnancy Outcomes in French Hemodialysis Patients.法国血液透析患者的妊娠结局。
Am J Nephrol. 2018;47(4):219-227. doi: 10.1159/000488286. Epub 2018 Mar 27.
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Antiangiogenic factors and maternal hemodynamics during intensive hemodialysis in pregnancy.
Hemodial Int. 2013 Oct;17(4):639-43. doi: 10.1111/hdi.12042. Epub 2013 Apr 1.

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