1PODOS Wound Care Clinic, Warsaw, Poland.
2Medical University of Warsaw, Chair and Department of Experimental and Clinical Pharmacology, Warsaw, Poland.
Pol J Microbiol. 2023 Jun 14;72(2):133-142. doi: 10.33073/pjm-2023-014. eCollection 2023 Jun 1.
Chronic wound infection is one of the factors that hinder or prevent its healing. The incidence of infection may vary depending on the type of wound. It is estimated that clinically significant infection in diabetic foot syndrome occurs in up to 30% of patients. Accurate diagnosis of infection features and proper microbiological tests are crucial for introducing of appropriate local and often systemic treatment. The aim of the study was a comparative analysis of the microbiota found in infected chronic wounds in patients from Poland, consulted on an outpatient basis at a wound care center in 2013-2021. The indication for microbiology culture tests was the detection of local signs of infection, and sampling was preceded by appropriate wound debridement. The standard culture technique was a deep-tissue biopsy. Material for the study was collected from 1,199 patients. Overall, 3,917 results of microbiological tests were subjected to retrospective analysis. The paper presents the results in the form of the number of cultured microorganisms and their relative incidence as percentages, considering the division into the types of wounds from which the material was obtained. The most frequently isolated microorganisms in the analyzed group were (14.3% of this group were MRSA - methicillin-resistant ) and (2.4% of this group were VRE - vancomycin-resistant ). Further analysis of such an extensive database, especially regarding drug susceptibility of isolated microorganisms, seems crucial to elaborate new recommendations for empirical antibacterial treatment of infected chronic wounds.
慢性伤口感染是阻碍或妨碍其愈合的因素之一。感染的发生率可能因伤口类型而异。据估计，糖尿病足综合征患者中临床上有意义的感染发生率高达 30%。准确诊断感染特征和进行适当的微生物学检查对于引入适当的局部和经常全身治疗至关重要。本研究的目的是对 2013 年至 2021 年在波兰接受门诊咨询的伤口护理中心的患者的感染性慢性伤口中发现的微生物群进行比较分析。微生物培养试验的指征是检测局部感染迹象，并且在适当的清创术之前进行采样。标准培养技术是深部组织活检。研究材料取自 1199 名患者。总体而言，对 3917 项微生物学检测结果进行了回顾性分析。本文以培养的微生物数量及其相对发生率（以百分比表示）的形式呈现结果，同时考虑了从获得材料的伤口类型进行分组。在分析组中最常分离到的微生物是 （该组中 14.3%为耐甲氧西林金黄色葡萄球菌）和 （该组中 2.4%为耐万古霉素肠球菌）。对如此广泛的数据库进行进一步分析，特别是关于分离微生物的药物敏感性，对于制定新的经验性抗菌治疗感染性慢性伤口的建议似乎至关重要。
