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小儿输尿管镜检查术治疗3岁以下小儿上尿路结石

Microureteroscopy in the treatment of upper urinary tract stones in pediatric patients younger than 3 years of age.

作者信息

Zhan Ruichao, Ge Yucheng, Liu Yukun, Zhao Zhenqiang, Li Jun, Wang Wenying

机构信息

Department of Urology, Beijing Friendship Hospital, Capital Medical University, 95 YongAn Road, Xicheng District, Beijing, 100050, China.

出版信息

Urolithiasis. 2023 Apr 4;51(1):64. doi: 10.1007/s00240-023-01435-5.

DOI:10.1007/s00240-023-01435-5
PMID:37014440
Abstract

The aim of this study is to evaluate the usefulness of microureteroscopy (m-URS) in the treatment of renal and ureteral stones in children younger than 3 years of age. A retrospective analysis of pediatric patients aged < 3 years with upper urinary tract calculi who underwent lithotripsy was performed. The children were divided into the m-URS group (4.85 F, n = 41) and the ureteroscopy (URS) group (4.5/6.5 F, n = 42) according to the type of ureteroscope used. The mean age of the patients was 23.5 ± 10.7 months in the m-URS group and 20.6 ± 7.1 months in the URS group (P = 0.212). The success rate of one-stage surgery was 80.5% (33/41) for m-URS and 38.1% (16/42) for URS (P < 0.001). The success rates of m-URS were 60.0%, 69.2%, and 91.3% for stones located in the renal pelvis/calix, upper ureter, and mid-lower ureter, respectively. Eight children in the m-URS group and 26 children in the URS group underwent the second-stage ureteroscopic surgery. The mean operation time was 50 (30-60) min in the m-URS group and 40 (34-60) min in the URS group (P = 0.287). The complication rates were 4.9% and 7.1% in the m-URS and URS groups, respectively (P = 1.000). The stone-free rate at 1 month after lithotripsy was 87.8% in the m-URS group and 83.3% in the URS group (P = 0.563). The mean anesthesia session was 2.1 in the m-URS group and 2.5 in the URS group (P = 0.002). M-URS can effectively reduce the number of anesthesia sessions and is considered an alternative treatment for upper urinary tract calculi in selected pediatric patients younger than 3 years of age.

摘要

本研究的目的是评估微通道输尿管镜检查(m-URS)在治疗3岁以下儿童肾及输尿管结石中的有效性。对年龄小于3岁的上尿路结石行碎石术的儿科患者进行回顾性分析。根据所使用的输尿管镜类型,将患儿分为m-URS组(4.85F,n = 41)和输尿管镜检查(URS)组(4.5/6.5F,n = 42)。m-URS组患者的平均年龄为23.5±10.7个月,URS组为20.6±7.1个月(P = 0.212)。m-URS一期手术成功率为80.5%(33/41),URS为38.1%(16/42)(P < 0.001)。位于肾盂/肾盏、上段输尿管和中下段输尿管的结石,m-URS的成功率分别为60.0%、69.2%和91.3%。m-URS组8例患儿和URS组26例患儿接受了二期输尿管镜手术。m-URS组平均手术时间为50(30 - 60)分钟,URS组为40(34 - 60)分钟(P = 0.287)。m-URS组和URS组的并发症发生率分别为4.9%和7.1%(P = 1.000)。碎石术后1个月的结石清除率,m-URS组为87.8%,URS组为83.3%(P = 0.563)。m-URS组平均麻醉次数为2.1次,URS组为2.5次(P = 0.002)。m-URS可有效减少麻醉次数,被认为是3岁以下特定儿科患者上尿路结石的一种替代治疗方法。

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本文引用的文献

1
Complication rate after pediatric shock wave lithotripsy according to Clavien-Dindo grading system: results from a systematic review and meta-analysis of the existing literature.根据Clavien-Dindo分级系统的小儿冲击波碎石术后并发症发生率:现有文献的系统评价和荟萃分析结果
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Micro-Ureteroscopy as a Treatment of Renal Pelvis Lithiasis in Young Children.小儿肾盂结石的微输尿管镜治疗
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Micro-ureteroscopy (m-URS) for treatment of upper ureteral stones in children: A new, different approach.
小儿上尿路结石的微输尿管镜治疗:一种全新的不同方法。
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General anesthesia affecting on developing brain: evidence from animal to clinical research.全身麻醉对发育中大脑的影响:来自动物到临床研究的证据。
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Outcomes of ureteroscopy (URS) for stone disease in the paediatric population: results of over 100 URS procedures from a UK tertiary centre.在英国的一个三级医疗中心,对 100 多例输尿管镜检查(URS)治疗儿童结石病的结果进行分析。
World J Urol. 2020 Jan;38(1):213-218. doi: 10.1007/s00345-019-02745-3. Epub 2019 Apr 4.
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Anesthesia Exposure in Children: Practitioners Respond to the 2016 FDA Drug Safety Communication.儿童麻醉暴露:从业者对 2016 年 FDA 药物安全通讯作出回应。
J Neurosurg Anesthesiol. 2019 Jan;31(1):129-133. doi: 10.1097/ANA.0000000000000545.
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Semi-Rigid Ureteroscopy Should Not Be the First Option for Proximal Ureteral Stones in Children.半硬性输尿管镜检查不应作为儿童近端输尿管结石的首选方法。
J Endourol. 2018 Nov;32(11):1028-1032. doi: 10.1089/end.2017.0925. Epub 2018 Oct 20.
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High prevalence of pediatric urinary tract stones in Xinjiang Uyghur.新疆维吾尔族儿童尿路结石高发。
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Micro-ureteroscopy vs. ureteroscopy: effects of miniaturization on renal vascularization and intrapelvic pressure.微输尿管镜与输尿管镜:微型化对肾血管化和肾盂内压的影响。
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Percutaneous nephrolithotomy versus retrograde intrarenal surgery for pediatric patients with upper urinary stones: a systematic review and meta-analysis.经皮肾镜碎石术与逆行性肾内手术治疗上尿路结石患儿:系统评价和荟萃分析。
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