Steinbuch M, Gaeuman J V
J Occup Med. 1986 Apr;28(4):276-81.
Between Jan 1, 1981, and Aug 31, 1983, 1,323 Ohio State University Hospital employees were screened for hepatitis B. There were 105 employees (cases) with present or past evidence of hepatitis B virus infection, and 210 randomly selected employees (controls) with no evidence of hepatitis B virus infection. Using logistic regression analyses to develop a risk index, the best predictive model indicated that nonwhites, males, discontinuity of employment, and frequency of contact with blood products constituted the most important risk factors in acquiring hepatitis B virus infections. Those with no blood product contact were at higher risk than those exposed to blood products. Thus, although there was a gradient of risk among those exposed to blood products, the findings suggest other factors may contribute more substantially to the risk than the exposure variables tested.
在1981年1月1日至1983年8月31日期间,对1323名俄亥俄州立大学医院的员工进行了乙肝筛查。有105名员工(病例)有目前或过去乙肝病毒感染的证据,210名随机挑选的员工(对照)没有乙肝病毒感染的证据。使用逻辑回归分析来制定一个风险指数,最佳预测模型表明,非白人、男性、就业间断以及接触血液制品的频率是感染乙肝病毒最重要的风险因素。未接触血液制品的人比接触血液制品的人风险更高。因此,尽管在接触血液制品的人群中存在风险梯度,但研究结果表明,其他因素可能比所测试的暴露变量对风险的影响更大。