Zhang Dayu School of Chemistry, Dalian University of Technology, Dalian 116024, P. R. China.
Org Biomol Chem. 2023 Apr 26;21(16):3350-3354. doi: 10.1039/d3ob00072a.
Herein, we report the generation of iminyl radicals through photocatalytic deoxygenation of oximes with trivalent phosphine. The hydroimination reaction proceeded β-scission of a phosphoranyl radical, followed by 5- cyclization of the resulting iminyl radical. This protocol transforms oximes, including alkyl oximes, into a variety of pyrrolines in moderate to good yields. A radical clock experiment confirmed the formation of a cyclic radical and supported our reaction design.
在此，我们报告了通过三价膦光催化肟的脱氧生成亚胺基自由基。氢亚胺化反应经历了磷自由基的 β 断裂，然后是生成的亚胺基自由基的 5-环化。该方案将肟（包括烷基肟）转化为中等至良好收率的各种吡咯啉。自由基钟实验证实了环状自由基的形成，并支持了我们的反应设计。
